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Allergy Drops Annual Cost: Yearly and Multi-Year Math

Annually, self-pay allergy drops total about $990 per year ($99 per month), while traditional clinics run roughly $1,200-$3,600 per year. Because a full sublingual immunotherapy course commonly lasts three to five years, the total cost of treatment typically lands between about $3,000 and $18,000 depending on provider, with telehealth at the lower end.

Medically reviewed by Dr. Chet Tharpe, MDUpdated

4 peer-reviewed sources

4 min read
Quick Answer

Allergy drops cost about $990 per year self-pay through telehealth, or roughly $1,200-$3,600 per year at a clinic. A full 3-5 year course totals several thousand dollars.

Medically reviewed by Dr. Chet Tharpe, M.D. ยท Last reviewed June 2026

Key facts

  • Self-pay sublingual immunotherapy drops run about $99/month or roughly $990 per year through telehealth providers.

    Provider pricing 2026

  • A full SLIT course typically lasts 3-5 years, putting the multi-year self-pay total in the range of about $3,500-$6,000.

    JAMA 2013 (Lin et al.)

  • Clinic allergy shots can total roughly $167-$417/month once injection visits and copays are added, far above telehealth drops.

    ACAAI / provider pricing 2026

  • Off-label compounded drops are generally not reimbursed by insurance but are HSA/FSA-eligible, lowering the net yearly cost.

    IRS Pub 502 / Johns Hopkins

$990/yr
SELF-PAY PER YEAR
$708/yr
INSURED CLINICAL/YR
$1.2-3.6k
CLINIC PER YEAR
3-5 yrs
FULL COURSE
01Overview

Thinking About Allergy Drops in Yearly Terms

While allergy drops are billed monthly, it helps to view the cost annually because sublingual immunotherapy is a multi-year treatment. Allergy drops are a custom liquid extract held under the tongue daily, designed to gradually reduce sensitivity to your specific triggers over time. Looking at the yearly total clarifies what you are committing to, since a single month's price can understate a course that often runs three to five years. Treatment begins with identifying your triggers, and Curex offers at-home allergy testing reviewed by a board-certified allergist to pinpoint your IgE triggers before the annual program is planned. Viewing the cost per year, and then across the full course, gives a realistic picture for budgeting and for comparing immunotherapy against the year-over-year cost of ongoing allergy medications.

Key Takeaway

An annual view reveals the true scale of immunotherapy, since the meaningful figure is the multi-year total, not a single month's price.

Real talk

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Curex's allergy drops are taken under the tongue at home, daily โ€” from $39/month with insurance (or $99/month self-pay), with no needles and no routine clinic visits.

Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.

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05Compare

Annual Drops Cost vs Annual Shots Cost

Compared year over year, allergy drops are usually less expensive than clinic allergy shots. Shots typically run $2,000 to $5,000 per year once per-visit copays and travel are counted, because they require ongoing in-office injections. Telehealth drops at roughly $708 to $990 per year avoid that visit burden. Drops also carry a lower risk of systemic reactions than shots, though both may reduce sensitivity over time and neither guarantees an outcome. Over a three to five year course, the annual difference compounds into meaningful savings, but the right choice still depends on your triggers, schedule, and how you respond to treatment.

Allergy Drops (per year)Best
Efficacy
Moderate evidence of symptom reduction
Duration
Commonly 3-5 years
Cost (5yr)
~$3,500-$5,000 self-pay
Convenience
Daily at home
Safety
Mostly mild local reactions
Allergy Shots (per year)
Efficacy
Well-established symptom reduction
Duration
3-5 years
Cost (5yr)
~$10,000-$25,000 with visits
Convenience
Regular clinic visits
Safety
Higher systemic reaction risk

Curex prices allergy drops at $39/month with insurance covering the clinical component, or $99/month which works out to $990 per year self-pay, keeping the annual cost well below typical clinic allergy shots. Allergy drops are compounded at a specialty pharmacy for each patient. The FDA does not review compounded products for safety or efficacy.

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07Pricing

Allergy Drops: Annual and Course Totals

On an annual basis, self-pay allergy drops through telehealth total about $990 per year, based on a $99 monthly rate. When insurance covers the clinical visit component, the telehealth out-of-pocket can be closer to $708 per year at the $39 monthly rate. Traditional clinics, billing the extract and visits separately, commonly run $1,200 to $3,600 per year. Because a full course lasts three to five years, the total cost of treatment typically lands between roughly $3,000 and $5,000 for telehealth self-pay, or higher at a clinic. Food allergy drops at about $99/month with insurance total near $1,188 per year. Compounded drops are off-label, so the extract is paid out of pocket, but all of these costs are HSA/FSA-eligible.

ItemWith InsuranceSelf-Pay
Telehealth Drops (per year)~$708/yr~$990/yr
Clinic Custom Drops (per year)Copays apply$1,200-$3,600/yr
Full 3-5 Year Course (telehealth self-pay)Lower with insured visits~$3,000-$5,000 total
Total$708/yr$990/yr

Cost Comparison

Telehealth Drops/yrBest value
$708-$990/yr
Clinic Drops/yr
$1,200-$3,600/yr
Clinic Shots/yr
$2,000-$5,000/yr
Costs to keep in mind
  • A one-time testing fee may apply outside the annual subscription
  • Clinic per-visit copays accumulate across the year
  • Stopping and restarting a course can add a repeat build-up cost
08Insurance

Insurance and the Yearly Allergy Drops Bill

Across a full year, most of your allergy drops spending will be out of pocket. Compounded liquid drops are off-label, so private insurance, Medicare, and Medicaid generally do not reimburse the extract for the year. With telehealth, the lower annual figure usually reflects insurance covering the clinical visits rather than the drops. Over a multi-year course, paying with HSA or FSA dollars is the most reliable way to lower your yearly net cost, since allergy drops are eligible for these pre-tax accounts. Some people set aside FSA funds each plan year specifically for immunotherapy. Because the commitment spans several years, mapping the annual cost against your HSA/FSA contributions helps with long-term planning.

Private InsuranceOff-label โš ๏ธ

Note: HSA/FSA-eligible

Drops off-label all year; clinical visits may be covered

MedicareOff-label โš ๏ธ

Compounded drops not reimbursed

MedicaidOff-label โš ๏ธ

Drops rarely covered; varies by state

Ways to pay
  • HSA/FSA eligible across plan years
  • Self-pay $990/yr
  • Insured clinical-visit rate ~$708/yr

Curex allergy drops start at $39/month with insurance (or $99/month self-pay) โ€” HSA/FSA eligible.

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09FAQ

Frequently asked questions

How much do allergy drops cost per year?

Self-pay allergy drops through telehealth total about $990 per year, based on a $99 monthly rate. When insurance covers the clinical visit component, the telehealth out-of-pocket can be closer to $708 per year at the $39 monthly rate. Traditional clinics generally run $1,200 to $3,600 per year once the separately billed extract and visit copays are added. Food allergy drops at about $99/month with insurance total near $1,188 per year. Because compounded drops are off-label, the extract is paid out of pocket, though the yearly cost is HSA/FSA-eligible. Your annual figure depends on your provider, your allergens, and your insurance.

What is the total cost of a full allergy drops course?

Because a sublingual immunotherapy course commonly lasts three to five years, the total cost of treatment matters more than any single year. For telehealth self-pay at about $990 per year, a full course totals roughly $3,000 to $5,000. At a traditional clinic running $1,200 to $3,600 per year, the multi-year total can climb considerably higher. Food allergy drops add to this since they are priced higher per month. These totals assume consistent, uninterrupted treatment, since durable benefit generally requires completing the course. There are no outcome guarantees, so it is wise to plan for the full multi-year commitment when budgeting.

Do allergy drops save money over years compared to medications?

Some people find that immunotherapy can be cost-competitive over many years compared with continually buying allergy medications, but it depends on your situation. Daily antihistamines, nasal sprays, and eye drops add up year after year and only mask symptoms, while immunotherapy may provide long-term relief by addressing the underlying allergic response. Allergy drops carry a meaningful annual cost during the three to five year course, after which ongoing medication spending may decrease for some patients. Because results vary and there are no guarantees, the long-term financial comparison is individual. Discussing realistic expectations with a board-certified allergist helps you weigh the multi-year math.

Can I pay for a year of allergy drops with my HSA or FSA?

Yes, you can generally use Health Savings Account or Flexible Spending Account funds to pay for a year of allergy drops, since they are a medical treatment for a diagnosed condition. Some people earmark FSA contributions each plan year specifically for immunotherapy, which uses pre-tax dollars and effectively lowers the annual net cost. Because compounded drops are off-label and rarely reimbursed by insurance, this pre-tax benefit is the most reliable way to reduce your yearly spend. Keep itemized receipts and any letter of medical necessity your provider supplies, and confirm eligibility details with your account administrator, since rules can vary slightly by plan.

Why might a clinic's annual allergy drops cost be higher?

A traditional clinic's annual allergy drops cost often runs higher than telehealth because the services are unbundled. Clinics typically bill the compounded extract and each follow-up visit separately, and per-visit copays accumulate across the year. Telehealth providers instead fold the testing review, extract, shipping, and care-team access into a flat monthly fee, which keeps the yearly total predictable and frequently lower. Location and the complexity of your allergen mix also influence clinic pricing. When comparing annual figures, ask the clinic for an all-in yearly estimate that includes the extract and expected visit copays, so you can fairly compare it against a telehealth subscription's annual cost.

How does the yearly cost change after the first year?

For most telehealth allergy drops programs, the yearly cost stays roughly stable across the course, since the flat monthly subscription continues at the same rate through build-up and maintenance. The first year may carry an extra one-time testing fee that does not recur, so some people find year one slightly higher than later years. At a clinic, annual costs can fluctuate with visit frequency, which sometimes eases after the early phase. Because durable benefit generally requires three to five years, plan for a similar yearly cost each year of the course. Modeling the full multi-year total, rather than just the first year, gives the most accurate budgeting picture.

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Curex allergy drops are a personalized sublingual extract, prescribed by a board-certified allergist and shipped to your door โ€” taken daily at home with no needles and no routine clinic visits. From $39/month with insurance, or $99/month self-pay. HSA/FSA eligible.

From $39/mo with insurance ยท No needles ยท HSA/FSA eligible ยท Cancel anytime

Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.

This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. Content reviewed by board-certified allergists at Curex.

Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.

The only FDA-approved sublingual immunotherapy products are tablets โ€” Grastek, Oralair, Ragwitek, and Odactra โ€” which are different from Curex drops.

Under-the-tongue allergy drops

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Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.

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