Sublingual Immunotherapy Cost: Clinic vs Telehealth
Sublingual immunotherapy (SLIT) costs vary by delivery model. Curex company treatment has plan-specific pricing (https://getcurex.com/learn/curex-pricing) with a $49 sign-up fee; insurance is accepted for allergy testing and consultations. Food and SCIT plan prices are listed in the canonical pricing record; confirm program eligibility and your personalized quote. Because liquid SLIT is off-label, the extract is rarely insurance-covered, though it is HSA/FSA-eligible.
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Curex company treatment has plan-specific pricing (https://getcurex.com/learn/curex-pricing) with a $49 sign-up fee; insurance is accepted for allergy testing and consultations. Food and SCIT plan prices are listed in the canonical pricing record; confirm program eligibility and your personalized quote. Liquid SLIT is off-label, so the extract is usually paid out of pocket.
Medically reviewed by Dr. Chet Tharpe, M.D. ยท Last reviewed June 2026
Key facts
Curex company treatment has plan-specific pricing (https://getcurex.com/learn/curex-pricing) with a $49 sign-up fee; insurance is accepted for allergy testing and consultations. Food and SCIT plan prices are listed in the canonical pricing record; confirm program eligibility and your personalized quote.
FDA-approved SLIT tablets (Grastek, Oralair, Ragwitek, Odactra) bill through the pharmacy benefit, while compounded drops are off-label and self-pay.
SLIT is backed by 60+ randomized controlled trials for reducing allergic rhinitis symptoms, with benefit generally needing 3-5 years.
Compounded drops are HSA/FSA-eligible even though they are off-label and not insurance-reimbursed.
Understanding the Cost of Sublingual Immunotherapy
Sublingual immunotherapy, or SLIT, is an allergy treatment in which a liquid allergen extract is held under the tongue for about two minutes daily, gradually retraining the immune response to your specific triggers. The clinical term covers both compounded liquid drops and FDA-approved tablets, and the cost differs sharply between them. For liquid drops, what you pay reflects three things: the allergy evaluation that identifies your sensitivities, the personalized extract, and ongoing provider oversight. Any immunotherapy begins with accurate testing, and Curex offers at-home allergy testing reviewed by a board-certified allergist to identify your IgE triggers before treatment is designed. Where you receive care matters most for price: a traditional allergist's office bills each element separately, while telehealth platforms package them into a single recurring fee.
SLIT cost is driven less by the medicine itself and more by your care model, with telehealth typically bundling services that clinics bill piecemeal.
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Curex allergy drops are taken under the tongue at home daily. Confirm your treatment quote; the company starting price is not a quote for every modality.
Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.
See if allergy drops are right for youSLIT vs Allergy Shots: A Cost Lens
Compared with subcutaneous immunotherapy, or allergy shots, SLIT shifts cost away from the clinic and toward a predictable home routine. Shots require regular in-office injections, generating travel and copay costs that often reach $167 to $417 per month. SLIT is self-administered at home, so the recurring expense is mainly the extract and oversight. SLIT also carries a lower risk of systemic reactions than shots, though both approaches may reduce sensitivity over time and neither is a guaranteed cure. For a full consumer-facing price breakdown, see the allergy drops cost pillar guide. The best value depends on your triggers and lifestyle, not the sticker price alone.
| Treatment | Efficacy | Duration | Cost (5yr) | Convenience | Safety |
|---|---|---|---|---|---|
SLIT (Allergy Drops)Best | Moderate evidence of symptom reduction | Commonly 3-5 years | ~$3,500-$6,000 self-pay | Daily at home | Mostly mild local reactions |
SCIT (Allergy Shots) | Well-established symptom reduction | 3-5 years | ~$10,000-$25,000 with visits | Regular clinic visits | Higher systemic reaction risk |
- Efficacy
- Moderate evidence of symptom reduction
- Duration
- Commonly 3-5 years
- Cost (5yr)
- ~$3,500-$6,000 self-pay
- Convenience
- Daily at home
- Safety
- Mostly mild local reactions
- Efficacy
- Well-established symptom reduction
- Duration
- 3-5 years
- Cost (5yr)
- ~$10,000-$25,000 with visits
- Convenience
- Regular clinic visits
- Safety
- Higher systemic reaction risk
Curex provides sublingual immunotherapy drops with plan-specific pricing (https://getcurex.com/learn/curex-pricing); insurance accepted for testing and consultations, a telehealth model that avoids the recurring visit costs of clinic-based care. Allergy drops are compounded at a specialty pharmacy for each patient. The FDA does not review compounded products for safety or efficacy.
See if allergy drops are right for youHow the Clinic and Telehealth Models Price SLIT
The biggest variable in sublingual immunotherapy cost is the care setting. In a traditional allergist's clinic, you typically pay separately for testing, the compounded extract, and follow-up visits. Once those add up, monthly costs commonly land between $100 and $300, and visit copays can stack on top. Curex company treatment has plan-specific pricing (https://getcurex.com/learn/curex-pricing) with a $49 sign-up fee; insurance is accepted for allergy testing and consultations. Food and SCIT plan prices are listed in the canonical pricing record; confirm program eligibility and your personalized quote. Because compounded liquid SLIT is off-label, neither model can usually bill the extract to insurance, so most of the spend is out of pocket regardless of setting. The difference is mostly transparency and convenience rather than dramatic price gaps in the medicine itself.
| Item | With Insurance | Self-Pay |
|---|---|---|
| Allergy Testing | May be covered at clinic | Confirm the current quote and any separately billed charges |
| Compounded SLIT Extract | Treatment is self-pay; insurance accepted for testing and consultations | Program quote required; confirm inclusions and separately billed charges |
| Follow-up Visits | Copays apply at clinic | Confirm the current quote and any separately billed charges |
| Total | Confirm testing and consultation coverage and patient responsibility | Program quote required; confirm inclusions and separately billed charges |
Cost Comparison
- Clinic SLIT often bills testing as a separate up-front charge
- Per-visit copays add to clinic totals
- FDA-approved SLIT tablets are priced as pharmacy drugs, separate from compounded drops
SLIT Insurance: Tablets vs Compounded Drops
Insurance treatment of sublingual immunotherapy hinges on whether you use FDA-approved tablets or compounded liquid drops. Tablets such as Grastek, Oralair, Ragwitek, and Odactra are FDA-approved single-allergen products and may be covered as pharmacy benefits with a copay. Compounded liquid drops, by contrast, are used off-label and are generally not reimbursed by private insurance, Medicare, or Medicaid. This is the single most important cost distinction in SLIT: the clinical route you choose determines whether insurance helps. For drops, the clinical visit component may be partially covered under medical benefits, and the treatment is HSA/FSA-eligible, letting you pay with pre-tax dollars.
Note: HSA/FSA-eligible
Liquid drops off-label; tablets may be covered as pharmacy benefit
Off-label compounded drops not reimbursed
Varies by state; drops rarely covered
- HSA/FSA eligible
- Curex company treatment has plan-specific pricing (https://getcurex.com/learn/curex-pricing) with a $49 sign-up fee; insurance is accepted for allergy testing and consultations. Food and SCIT plan prices are listed in the canonical pricing record; confirm program eligibility and your personalized quote.
- Pharmacy benefit for FDA-approved tablets (separate product)
Compare Curex plan pricing and additional charges. Insurance can be billed for testing and consultations; confirm your benefits and written treatment quote.
Start free assessmentFrequently asked questions
What is the average cost of sublingual immunotherapy?
The average cost of sublingual immunotherapy depends heavily on whether you use compounded liquid drops or FDA-approved tablets, and where you receive care. Curex company treatment has plan-specific pricing (https://getcurex.com/learn/curex-pricing) with a $49 sign-up fee; insurance is accepted for allergy testing and consultations. Food and SCIT plan prices are listed in the canonical pricing record; confirm program eligibility and your personalized quote. FDA-approved tablets are priced as pharmacy drugs and may carry a copay if covered. Because liquid drops are off-label, most of the cost is out of pocket. Your individual price varies with your allergens, your provider, and your insurance plan's handling of the clinical components.
Is sublingual immunotherapy covered by insurance?
Coverage depends on the product. FDA-approved sublingual tablets such as Grastek, Oralair, Ragwitek, and Odactra are prescription drugs and may be covered under a pharmacy benefit, subject to a copay. Compounded liquid SLIT drops are used off-label and are generally not covered by private insurance, Medicare, or Medicaid, so the extract is usually paid out of pocket. The clinical components like testing and provider visits may be partially covered under your medical benefits. Sublingual immunotherapy is also HSA/FSA-eligible, allowing you to pay with pre-tax dollars and reduce your effective cost.
Why is clinic SLIT more expensive than telehealth?
Clinic sublingual immunotherapy often appears more expensive because the costs are unbundled. A traditional allergist's office charges separately for the allergy evaluation, the compounded extract, and each follow-up visit, with copays added on. Telehealth providers instead package the testing review, the personalized extract, shipping, and care-team access into a single flat monthly subscription, which makes the total more predictable and often lower. The underlying medicine is similar; the difference is largely in how services are billed and whether you must travel for visits. Always compare what each program actually includes before judging which is cheaper for your situation.
How long do you pay for sublingual immunotherapy?
Most sublingual immunotherapy courses run about three to five years, because durable benefit generally requires sustained treatment that gradually retrains the immune response. That means the monthly cost is a multi-year commitment rather than a short-term purchase. Some people notice symptom changes within the first year, but stopping early can reduce the long-term benefit. Because the treatment is taken daily at home, consistency matters for both results and getting value from your spending. There are no outcome guarantees, so it is worth discussing a realistic treatment timeline and total expected cost with a board-certified allergist before committing.
Are compounded SLIT drops the same as FDA-approved tablets?
No. Compounded liquid SLIT drops are custom-mixed multi-allergen extracts used off-label, meaning the sublingual route for these compounded products is not FDA-approved. FDA-approved sublingual tablets are single-allergen prescription drugs, such as Grastek for timothy grass or Odactra for dust mites, that went through formal approval. The two differ in regulatory status, formulation, and how insurance handles them: tablets may be covered as pharmacy benefits, while drops are generally an out-of-pocket cost. Both deliver allergen under the tongue, but they are not interchangeable, and your provider will recommend the option suited to your specific allergy profile.
What questions should I ask before paying for SLIT?
Before committing to sublingual immunotherapy, ask the provider for an all-in cost rather than just a base price. Find out whether the initial allergy testing is included or billed separately, what the monthly fee covers, and whether the figure assumes insurance covers any clinical component. Ask about the expected length of the course, since most run three to five years, and what happens to cost if you pause. Confirm whether the treatment is HSA/FSA-eligible and whether they provide itemized receipts. Finally, ask how the care team supports dose adjustments. These questions reveal the true multi-year cost and help you compare clinic and telehealth options fairly.
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Coverage for sublingual immunotherapy splits by product: FDA-approved tablets are often covered, compounded liquid drops usually are not. Full breakdown.
Read moreQuestions about Curex itself?
Straight answers about the company, the evidence, what patients report, and what it costs โ including the parts that are not flattering.
Treat your allergies โ drops under the tongue.
Curex allergy drops are a personalized sublingual extract, prescribed by a board-certified allergist and shipped to your door โ taken daily at home with no needles and no routine clinic visits. Confirm your current treatment quote. HSA/FSA eligible.
Confirm your quote ยท Remaining payments for shipped treatment are collected on cancellation
Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.
- 1American College of Allergy, Asthma & Immunology (ACAAI), Sublingual Immunotherapy (SLIT)
- 2Lin SY, Erekosima N, Kim JM, et al. Sublingual immunotherapy for the treatment of allergic rhinoconjunctivitis and asthma: a systematic review. JAMA. 2013;309(12):1278-1288.
- 3American Academy of Allergy, Asthma & Immunology (AAAAI), Sublingual Immunotherapy overview
- 4U.S. Food and Drug Administration, Allergenics (FDA-approved sublingual tablet products)
This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. Content reviewed by board-certified allergists at Curex.
Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.
The only FDA-approved sublingual immunotherapy products are tablets โ Grastek, Oralair, Ragwitek, and Odactra โ which are different from Curex drops.