EOB image redacted
BCBS PPOOH
Typical clinic allergy-shot maintenance visit — $30 copay, repeated week after week, adds up fast.
- Billed by provider
- $184
- Insurance paid
- $142
- Patient owed
- $42
Representative · PayerPrice BCBS 95117 nat'l avg
AI-powered · 142+ articlesAllergy drops shipped to your door
Allergy drops, shipped to your door.
Personalized sublingual immunotherapy, prescribed by board-certified clinicians and shipped to your door. Ask anything — get a clear answer from our library in seconds.
100+
Clinical studies
50,000+
Patients treated
<0.1%
Systemic reactions
Under tongue
Daily dose
12,000 patients treated0 just got matched today53 patients started today
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from $39/mo with insurance·$99/mo self-pay·HSA/FSA eligible
Available in every state · Prescribed by board-certified clinicians. Allergy drops are compounded at a specialty pharmacy for each patient. The FDA does not review compounded products for safety or efficacy.
Most read · This week
What patients ask about most.
Cost & Insurance
How much do allergy drops cost?
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Cost & InsuranceAre allergy drops covered by insurance?
Read article
Side EffectsWhat are the side effects?
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GuidesHow long do allergy drops take to work?
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GuidesDo allergy drops actually work?
Read article
Drops vs ShotsAllergy drops vs shots
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Drops vs ShotsDrops vs FDA-approved tablets
Read article
Knowledge library
142 evidence-backed articles.
Every guide draws on over 100 clinical studies of sublingual immunotherapy — including the Lin et al. 2013 JAMA systematic review and Cochrane reviews — and is reviewed by board-certified allergists.
Guides & FAQ
65 articlesComprehensive guides on how sublingual allergy drops (SLIT) work, what to expect, and who they may suit.
- How Do Allergy Drops Work? The Immunology of SLIT
- Are Allergy Drops Effective? Understanding the Evidence Quality
- How To Get Allergy Drops: A Step-by-Step Guide
- Do Allergy Drop Results Last After You Stop?
Side Effects
34 articlesWhat to expect from drops — mostly mild, local oral reactions, safety timelines, and when to seek care.
- Allergy Drops Side Effects: What to Expect From First Dose to Maintenance
- Can Allergy Drops Cause Anaphylaxis?
- Allergy Drops Side Effects in Adults
- Allergy Drops and Mouth Swelling: Local or Concerning?
Cost & Insurance
27 articlesReal pricing — from $39/mo with insurance or $99/mo self-pay, plus how HSA/FSA coverage works.
- Allergy Drops vs Allergy Shots: A Cost Comparison
- Are Allergy Drops FSA Eligible?
- Allergy Drops Monthly Cost: The Subscription Model
- Food Allergy Drops Cost: Pricing Food SLIT
Drops vs Shots & Alternatives
16 articlesHow sublingual drops compare to allergy shots (SCIT) and FDA-approved SLIT tablets — risk, convenience, and evidence.
- Allergy Drops vs Shots: An Honest, Evidence-Based Comparison
- Are Allergy Drops as Effective as Allergy Shots?
- Allergy Drops vs Oral Immunotherapy: Which One Are You a Candidate For?
- SLIT vs SCIT: Definitions, Evidence Base, and Safety Differential
Over 100 clinical studies
Sublingual immunotherapy evidence base
50,000+ patients treated
Across the Curex program
<0.1% systemic reactions
In Curex’s program
Prescribed by clinicians
Board-certified · compounded for you
Safety first
Built around your safety.
Sublingual immunotherapy has a well-documented safety profile, with side effects that are mostly mild and local. Curex pairs that with board-certified allergist oversight, a personalized compounded extract, and care-team support — so you always know what to expect.
- 01Board-certified allergist oversightA licensed allergist reviews your intake and oversees your treatment plan — the same physician oversight you would expect from an in-clinic immunotherapy program.
- 02Personalized, compounded extractYour drops are compounded from standardized allergen extracts and matched to your specific triggers. Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy.
- 03Gradual, at-home dosingDrops are taken under the tongue daily, as directed by your provider. Your provider sets and adjusts your dosing schedule over time.
- 04Supervised first dose + care-team accessYour first dose is taken with provider supervision, and your care team is reachable for questions about dosing, reactions, or missed days. (Specific supervision details are confirmed during intake.)
- 05Mostly mild, local side effectsSLIT is generally well tolerated; most side effects are mild and local — itchy mouth, throat or ears, mild mouth/tongue swelling, or minor stomach upset, often easing as tolerance builds. Systemic reactions are uncommon — under 0.1% in Curex’s program. Your allergist will discuss whether an epinephrine auto-injector is appropriate for you.
When to seek emergency care
Throat tightness, difficulty breathing, widespread hives, or lightheadedness after a dose — call 911 immediately. Serious systemic reactions to SLIT are exceptionally rare (anaphylaxis on the order of 1 per 100 million doses, with no SLIT fatalities reported worldwide), but they are not impossible. Eosinophilic esophagitis and uncontrolled or severe asthma are contraindications — discuss your full history with your allergist.
The science
How immunotherapy retrains your immune system.
Unlike antihistamines that mask symptoms, sublingual immunotherapy addresses the underlying allergic response. Tiny doses of your specific allergens, held under the tongue daily over time, can help the immune system stop overreacting — inducing regulatory T cells and IgG4 blocking antibodies (Lin et al. 2013 JAMA systematic review: moderate-grade evidence).
Treg induction over time
Th2 (allergy)Treg (tolerance)IgG4 (blocking)
Stylized — actual immune shifts vary by allergen and individual response. Durable benefit typically requires a multi-year course.
01
Allergen Testing
IDENTIFY TRIGGERS
A board-certified allergist reviews your profile to pinpoint the allergens most likely driving your symptoms.
02
Custom Drops
PERSONALIZED EXTRACT
A personalized liquid allergen extract is compounded for you and shipped to your door — matched to your specific allergen profile.
03
Daily Under the Tongue
BUILD TOLERANCE
You place the drops under your tongue for about 2 minutes once a day at home — no needles — gradually exposing your immune system to your triggers.
04
Immune Retraining
UNDERLYING RESPONSE
Over time, immunotherapy can shift the immune system from IgE-driven overreaction toward regulatory T cells and IgG4 blocking antibodies — addressing the underlying allergic response.
05
Long-Term Relief
OVER 3–5 YEARS
With a typical 3–5 year course, many patients experience lasting improvement. Benefit and durability vary by individual.
How it works
From quiz to your door in days.
No clinic visits. No waiting rooms. No needles. A board-certified allergist personalizes your drops and ships everything to your door.
01
Take the Quiz
Two minutes of questions about your triggers, symptoms, and history.
02
Allergist Review
A board-certified allergist reviews your case, determines eligibility, and personalizes your sublingual drops. Provider oversight continues throughout your program — not just at intake.
03
Drops Ship to You
Your personalized liquid extract arrives at your door with simple instructions — no syringes, no needles.
04
Daily Drops at Home
Place the drops under your tongue for about 2 minutes once a day, as directed by your provider. No routine office visits.
Supervised first dose
Your first dose is taken with provider supervision so your care team can confirm you tolerate it well. After that, you take your drops at home, daily, as directed by your provider. Allergy drops are compounded at a specialty pharmacy for each patient. The FDA does not review compounded products for safety or efficacy.
Available in every state. Eligibility is confirmed during your intake at getcurex.com.
Drops vs Shots
Allergy drops vs shots — same goal, no needles.
Both sublingual drops (SLIT) and allergy shots (SCIT) retrain the immune system. Drops are taken at home under the tongue and carry a lower risk of systemic reactions than shots — though shots have the deepest RCT evidence base. A board-certified clinician helps you choose.
Feature
This hub
Curex Drops
Clinic Allergy Shots
No needles — taken under the tongue
Drops
Injection
Done at home, no routine office visits
At home
Clinic visits
Systemic reactions
<0.1%
Higher risk
Dosing convenience
Daily at home
Weekly visits
Care-team messaging access
Included
Office hours
Strongest RCT base for severe cases
Good evidence
Best evidence
Typical out-of-pocket
$39/mo–$99/mo
$167–$417/mo
How it’s supplied
Compounded for you
Clinic-mixed extracts
HSA / FSA eligible
Yes
Yes
Covered by most insurance
Usually not
Often partial
The <0.1% systemic-reaction figure reflects Curex's program. Allergy drops are compounded at a specialty pharmacy for each patient, and the FDA does not review compounded products for safety or efficacy. The only FDA-approved SLIT products are tablets (Grastek, Oralair, Ragwitek, Odactra), which are different from Curex drops.
Real cost transparency
What clinic allergy care actually costs.
Most articles quote vague ranges. We show de-identified explanation-of-benefits documents from in-clinic allergy care — what was billed, what insurance paid, what the patient owed.
EOB image redacted
HOPDMNREAL CASE
Hospital outpatient department billed 40-allergen skin testing at $24,400 — 30× the typical fee.
- Billed by provider
- $24,400
- Insurance paid
- $19,000
- Patient owed
- $5,400
REAL · Kaitlin Johnson · PBS NewsHour 2024
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Anthem PPOCAREAL CASE
119-allergen patch test at Stanford. Anthem accepted the inflated billed amount as in-network.
- Billed by provider
- $48,329
- Insurance paid
- $11,000
- Patient owed
- $3,103
REAL · Janet Winston · KFF Health News / NPR
Curex drops are predictable — from $39/month with insurance or $99/mo self-pay, versus roughly $167–$417/mo for in-clinic shots. The compounded drops themselves are not billed to insurance but are HSA/FSA-eligible.
Real cost · No surprises
What allergy drops actually cost.
Compare a 3-year run of Curex sublingual drops — $39/month with insurance or $99/mo self-pay — against typical in-clinic allergy shots, which run roughly $167–$417/mo out of pocket.
Interactive CalculatorLive
$167$417
In-clinic shots — 3 years
weekly visits
- Out-of-pocket ($250/mo)
- $9,000
- Clinic visits & travel
- Extra
3-year total
$9,000
Saves $7,596
Curex drops — 3 years
0 commutes
- Subscription ($39/mo)
- $1,404
- Clinic time (at home)
- $0
3-year total
$1,404
You save with Curex drops
$7,596 over 3 years
Plus no weekly commutes · taken at home · HSA/FSA eligible
In-clinic shot range ($167–$417/mo) per Curex's own homepage comparison. The compounded drops themselves are not billed to insurance; the from-$39/mo figure reflects insurance covering the clinical-visit component. Estimate only — your costs depend on your plan and provider.
Pricing
At-home drops. Predictable price.
Curex sublingual drops are from $39/month when insurance covers the clinical-visit component, or $99/mo self-pay. The compounded drops themselves are not billed to insurance but are HSA/FSA-eligible. Food SLIT is $99/month.
Self-pay · Pay monthly
$99/mo
Self-pay · cancel anytime
from $39/mo with insurance
- Personalized sublingual drops (SLIT)
- Board-certified allergist review
- Extract compounded & shipped to your door
- Unlimited care-team messaging
- Dose adjustments as directed by your provider
- HSA / FSA eligible
BEST VALUE
Self-pay · Billed yearly
$990/yr
That's just ~$82.50/mo — our lowest price.
Far less than typical in-clinic shots ($167–$417/mo)
- Everything in Monthly
- Effective ~$82.50/mo when paid yearly
- Priority shipping on all refills
- Lock in this price for 12 months
- $39/mo option when insurance covers the clinical visit
- HSA / FSA eligible
Common questions
Everything you need to feel confident.
Sublingual immunotherapy (SLIT) uses tiny, personalized doses of your specific allergens held under the tongue for about 2 minutes, once a day at home. Over months, this can help the immune system shift from an IgE-driven overreaction toward regulatory T cells and protective IgG4 blocking antibodies — addressing the underlying allergic response. A 2013 JAMA systematic review of 63 randomized trials (Lin et al.) found moderate-grade evidence that SLIT reduces rhinitis and rhinoconjunctivitis symptoms.
Ready to start?
Allergy drops at home. From $39/mo with insurance.
Your personalized sublingual drops, prescribed by board-certified clinicians and shipped to your door. No needles. No clinic visits. Cancel anytime.
Get StartedYour plan is reviewed by a board-certified allergist. Allergy drops are compounded at a specialty pharmacy for each patient. The FDA does not review compounded products for safety or efficacy.
HIPAA compliant
FDA-registered pharmacy
USP <797> compounding
HSA / FSA eligible
256-bit SSL secured
This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. Content reviewed by board-certified allergists at Curex.
Start today
Allergy relief.
No needles.
Personalized sublingual drops, prescribed by board-certified clinicians and taken at home, daily. No shots. No clinic visits. From $39/mo with insurance. Start with a 2-minute quiz.
from $39/mo with insurance · $99/mo self-pay · HSA / FSA eligible · Cancel anytime
Available in every state. Prescribed by board-certified clinicians. Allergy drops are compounded at a specialty pharmacy for each patient. The FDA does not review compounded products for safety or efficacy.