Your shot journey, mapped out.
Scrub through the 3-to-5-year protocol — from build-up week one to long-term resolution — and see exactly what to expect at each phase.
Scrub through your 3 to 5-year journey.
Click any phase to see what happens and which articles cover it.
Build-up starts.
Weekly injections with escalating doses. Your immune system meets the allergen at a controlled pace.
All articles
Allergy Shots: Complete SCIT Guide for Patients | Curex
Allergy shots (SCIT) reduce symptoms by 33-85% over 3-5 years. Learn how they work, what they cost, and who qualifies for this disease-modifying treatment.
Allergy Shots for Cat Allergy | Full SCIT Guide | Curex
Allergy shots for cat allergies reduce symptoms 60-72% at the 15 mcg Fel d 1 maintenance dose. Cat SCIT efficacy, dosing, and alternatives.
Do Allergy Shots Work? Evidence & Honest Verdict | Curex
Do allergy shots work? Meta-analyses of 51 RCTs show 33-85% symptom reduction — but 20-50% of patients are low responders. Here's the honest evidence.
Long-Term Side Effects of Allergy Shots | Safety | Curex
Long-term side effects of allergy shots: aluminum exposure, organ safety, fatigue, and post-treatment durability reviewed with real surveillance data.
How Do Allergy Shots Work? Immune Mechanism | Curex 2025
Allergy shots work through IgG4 blocking antibodies and regulatory T cells. Full science-backed explanation of the molecular cascade behind SCIT.
Allergy Shots Side Effects: Full Spectrum Guide | Curex
Allergy shots side effects: local redness to rare anaphylaxis. WAO grades, reaction rates, risk factors, and when to seek emergency care explained.
How Much Do Allergy Shots Cost? Prices by Payer | Curex
Allergy shots cost $20-$100 per visit depending on insurance. See Medicare, commercial, and self-pay costs across a full 3-5 year treatment course.
Allergy Shots for Adults: No Age Ceiling or Limit | Curex
Allergy shots work for adults of all ages, including over 60. Learn efficacy, polypharmacy considerations, and long-term remission data for adult SCIT.
Allergy Shots Cost: Full CPT-Level Pricing Breakdown | Curex
Allergy shots cost $1,000-$4,000/year self-pay. See every CPT code — 95004, 95165, 95115, 95117 — with Medicare, commercial, and cash prices side by side.
Is Allergy Shot Treatment Covered by Insurance? | Curex
Yes — every major insurer covers in-office allergy shots without prior auth. See copay exposure, Medicare math, Medicaid gaps, and HSA eligibility rules.
Allergen Desensitization: SCIT, SLIT & OIT Guide | Curex
Allergen desensitization covers SCIT, SLIT, OIT, and EPIT. Compare safety profiles, evidence bases, and regulatory status before choosing your approach.
Allergy Shots vs Drops: Evidence-Based Comparison | Curex
Allergy shots (SCIT) vs sublingual drops (SLIT): comparable efficacy per Nelson 2015, but SLIT has zero fatalities vs 1 per 2.5M shots. Full comparison.
SCIT Allergy Treatment — Patient Decision Guide | Curex
SCIT (subcutaneous immunotherapy) has SMD -0.73 efficacy across 51 RCTs and three protocol options. Clinical guide for patients evaluating allergy shots.
Allergy Shots for Mold Allergy | Alternaria Evidence | Curex
Allergy shots for mold: only Alternaria has high-quality evidence (63.5% CSMS reduction by year 3). Cladosporium limited data. Extract quality critical.
Allergy Shots for Children: Safety and Efficacy | Curex
Allergy shots for children prevent asthma (OR 2.52, PAT study). Age requirements, pediatric SCIT efficacy, and asthma prevention for ages 5-17.
Subcutaneous Immunotherapy (SCIT): Clinical Guide | Curex
SCIT uses FDA-regulated allergen extracts at 5-20 mcg major allergen per dose. Clinical reference on dosing units, extract standards, and protocols.
Allergy Shots for Dust Mite Allergy | Full HDM SCIT Guide
Dust mite allergy shots have the strongest perennial SCIT evidence: symptom SMD -0.95, 55% asymptomatic at 10 years. Der p 1 dosing targets inside.
Allergy Shots for Asthma: Symptoms and Evidence | Curex
Allergy shots for asthma reduce symptoms (SMD -0.59) and medication use (SMD -1.21) but not FEV1. FEV1 below 70% is a contraindication.
Allergy Shot Reactions: Signs, Grades & What to Do | Curex
Allergy shot reactions explained by WAO grade: recognize each level, know when to use epinephrine, and understand biphasic reaction risk.
Missed Allergy Shot: What to Do Now | Dose Guide | Curex
Missed an allergy shot? Dose adjustments depend on gap length: under 2 weeks continue normally, 90+ days restart from bottle 1. Full dose tables inside.
Allergy Shots During Pregnancy: Safety & Guidelines | Curex
Allergy shots during pregnancy: continuing maintenance SCIT is acceptable, but initiating is contraindicated. Swedish registry of 743 pregnancies.
Are Allergy Shots Worth It? Cost-Benefit Analysis | Curex
Are allergy shots worth it? Allergy shots saved 33% on total healthcare costs vs. controls at 18 months. Here is the full ROI framework for 2025.
Allergy Immunotherapy Shots: Schedule & Results | Curex
Allergy immunotherapy shots require 57-60 clinic visits over 3 years — about 110 hours. Your complete visit-by-visit guide from build-up to lasting relief.
How Long Do Allergy Shots Last? | Full SCIT Duration Guide
How long do allergy shots last? Treatment takes 3-5 years; benefits last 7-12 years after stopping. SCIT duration, remission, and durability data.
Allergy Shots Schedule: Frequencies & Protocols | Curex
Allergy shots schedule: build-up 1-2x/week for 3-6 months, then maintenance every 2-4 weeks for 3-5 years. Conventional, cluster, and rush protocols.
Allergy Shots Success Rate: What Research Shows | Curex
Allergy shots success rate: 50-80% overall, but grass pollen reaches 85% and cockroach SCIT just failed its phase III trial. Full per-allergen data inside.
Skip the surprise bills. Pay one flat rate.
Curex's flat $129/month covers everything — board-certified allergist design, FDA-registered pharmacy serum, weekly at-home delivery. No copays, no facility fees, no surprises. HSA/FSA eligible.
From $129/mo · Save 46% on annual · HSA/FSA eligible · Cancel anytime