How to read a 99% success rate

Not just Food Allergy Institute’s — anyone’s. Three questions price every outcome claim in this market, and we apply them to our own numbers on this page too.

Short answer

The figure is real in the sense that Food Allergy Institute publishes it: “99% success rate after completing TIP,” alongside a sub-1% reaction rate, 56,000+ food challenges and introductions annually, and 130+ allergens assessed. Three things determine how much weight it carries. The denominator: completers of a 2.5-to-4-year program, not starters — and completion rates are unpublished. The verification: self-reported, with the main supporting study a 51-patient retrospective without a control group, reportedly declined by more than six larger journals before publication. And the definition: “success” is the clinic’s own endpoint, “food freedom,” which no other program measures the same way. A 2021 Undark investigation quoted academic allergists who found the figure implausible; thousands of families report real graduations. Both facts stand. Curex’s answer to the same three questions is on this page: the treatment it prescribes has NIH-funded, peer-reviewed trials behind it, and its program-level figures are internal. Curex is the only fully at-home food allergy program in the US.

Medically reviewed by Dr. Neeta Ogden, MD, FACAAI · Last reviewed September 2026

What the clinic publishes

Food Allergy Institute’s Tolerance Induction Program (TIP) is one of the two leading in-person food allergy programs in the country. These are the figures on its own website, checked September 2026.

“success rate after completing TIP” — their wording
99%“success rate after completing TIP” — their wording
reported reaction rate for the duration of TIP
<1%reported reaction rate for the duration of TIP
food challenges and introductions reported annually
56,000+food challenges and introductions reported annually
allergens assessed under the protocol
130+allergens assessed under the protocol
typical program length; complex cases run longer
2.5–4 yrstypical program length; complex cases run longer
patients in the main supporting publication
51patients in the main supporting publication

Competitor figures are what each provider published on its own site or what patients reported publicly, dated where checked. Prices and policies change — confirm current figures with each provider, including us, before enrolling.

What “after completing TIP” measures

Three questions that price any success rate

These work on FAI’s 99%, Latitude’s 94–98%, and anything Curex tells you. Ask all three of every provider.

What journalists, experts, and reviewers found

Graduations and attrition, side by side

Both columns are real, both are attributed, and neither cancels the other. All items are individual patient or parent reports from public threads and reviews — anecdotes, not data.

Reported graduations

The outcomes families describe

  • Multi-allergen tolerance“My son now can eat whole egg, 4 oz milk, and 16 peanuts” — one parent’s report of results in progress.
  • Durable remission“Graduated a year ago and freely eats everything”; another patient: “in remission for 5 years, I can eat anything.”
  • On-schedule completionA family reporting a “food freedom visit” scheduled after 2.5 years — the fast end of the published range.
  • Loyalty to the founderTeens and adults report saving money to attend; “Dr. R is a legend” is a representative quote from the positive cluster.
Reported attrition and friction

Why some families stop or struggle

  • Unpublished dropout rateLong-time observers say many families quit and attrition data is not released. No public figure exists either way.
  • EoE during treatmentOne documented dropout: a child developed eosinophilic esophagitis during dairy treatment — a known risk of oral immunotherapy generally.
  • Restarts for new allergensFamilies report redoing completed allergens (peanut, almond) as a prerequisite for treating new ones (cashew, pistachio).
  • Post-remission feesSeveral families report an annual maintenance fee of roughly $4,000 after reaching remission, described as not disclosed until they asked directly.

Published outcome claims, side by side

The same three questions applied across the market. Timeframes and endpoints differ, so read across each row rather than down the percentage column.

What it costs to stay in the denominator

Our numbers, priced identically — and where the facts point

What they offer

What this provider is known for, from the public record.

  • Clinic oral immunotherapy

    Faster, larger threshold rise

    In the one head-to-head peanut trial in children, oral immunotherapy raised the reaction threshold roughly 141-fold at 12 months against roughly 22-fold for sublingual drops (with more side effects and withdrawals).

    Source: Narisety 2015, PMID 25528358

  • Food Allergy Institute

    Supervised pace

    In-person supervision at 4–6 visits a year permits a pace no at-home program should attempt; the clinic publishes typical completion in 2.5–4 years.

    Source: foodallergyinstitute.com

  • Food Allergy Institute

    Food challenges built in, complex cases

    Supervised food challenges and introductions are part of the program rather than referred out, for ages 15 months to 50 years, including complex multi-allergen cases.

    Source: foodallergyinstitute.com

How food allergy drops are regulated

Personalized allergy drops are compounded for each individual patient. Such formulations are not reviewed by the FDA. However, they remain common practice for allergists and ENT allergists because they provide a convenient alternative to allergy shots. Allergy drops are the standard of care in many EU countries.

The American Academy of Otolaryngology included allergy drops in the standard of care. The FDA has approved four sublingual tablets for single allergens; allergy drops are compounded, target multiple allergies at once, and remain off-label.

Has the FDA written to Curex about allergy drops? Once, in 2021: an untitled letter about how the drops were marketed. Curex changed its website, responded in April 2021, and has had no FDA correspondence about allergy drops since.

Does the 2025 FDA warning letter concern allergy drops? No. The September 2025 warning letter concerned marketing language for compounded GLP-1 weight-loss products; Curex made the requested changes.

Every letter and response: Curex and the FDA. The short version: Is Curex legit?

The practical next step

Frequently Asked Questions

If you experience sudden difficulty breathing, throat swelling, or other signs of anaphylaxis, call 911. A prescribed epinephrine auto-injector is the first-line treatment — not antihistamines.

This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. Content reviewed by board-certified allergists at Curex.

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