Curex
Explainer

Latitude’s program, in plain terms

Diagnose by food challenge, up-dose under frequent supervision, maintain for life. Here is each step with the published numbers, the patient-reported costs, and the daily rules attached.

Short answer

Latitude Food Allergy Care runs a conventional, well-documented in-clinic arc: diagnosis built on oral food challenges (the gold standard), supervised up-dosing visits at the frequent cadence OIT up-dosing requires for a published 6–12 months (average about 8.4), then lifelong maintenance dosing. Multi-allergen OIT is offered, adults case by case. Diagnostics and visits are typically covered in-network; the one-time program fee is not, and patients report $4,000 to over $5,000 depending on region. The published outcomes are strong — 94% of patients of all ages desensitized, per Latitude's internal 2026 data — and the third-party record is unusually clean. The constraint is the map and the calendar: roughly 12 offices, all in coastal California and greater New York, plus OIT's daily rules for the duration. Families the map or the calendar rules out have the right place to start in the only fully at-home program. Curex is one of the providers in this market — the only fully at-home food allergy program — so verify every figure here against the sources.

Medically reviewed by Dr. Chet Tharpe, M.D. · Last reviewed September 2026

The arc

The program in numbers

published active phase, up-dosing to maintenance
6–12 mopublished active phase, up-dosing to maintenance
between supervised clinic visits during up-dosing
1–2 wkbetween supervised clinic visits during up-dosing
offices, all in coastal California and greater New York
~12offices, all in coastal California and greater New York
patient-reported one-time program fee, not covered by insurance
$4,000–$5,000+patient-reported one-time program fee, not covered by insurance

Figures are what Latitude published on its own site or what patients reported publicly, checked September 2026. Prices and policies change; confirm current figures with each provider, including us, before enrolling.

Step one

A diagnosis built on food challenges

Latitude's program starts with testing, and testing at Latitude means more than a skin prick. The clinic runs oral food challenges, the gold standard of food allergy diagnosis: the patient eats gradually increasing amounts of the suspect food under medical observation until a reaction occurs or a target dose is reached. It is the only test that answers the question families actually have, which is what happens if my child eats this.

Challenges cut both ways, and that is their value. Some confirm an allergy and set a baseline for treatment. Others remove it: parents on Park Slope Parents describe Latitude's challenges as life-changing for freeing children from avoidance diets built on false-positive test results, with one writing that they trust Latitude to be more discriminate and thorough.

One fair note: oral food challenges happen in a clinic on every protocol, including for Curex patients. No at-home program replaces that step, and none should claim to.

Step by step

The arc from first visit to maintenance

Latitude's shape is the conventional OIT arc, executed with more published detail than most clinics provide.

PhaseWhat happensTimeline
Testing and diagnosisSkin and blood testing plus oral food challenges where indicated; challenges can also remove false-positive allergy labelsFirst visits
Up-dosing (active phase)Supervised dose escalation in clinic at the frequent cadence OIT up-dosing requires, with daily home dosing between visits; multi-allergen OIT offered6–12 months published; ~8.4-month average
MaintenanceRegular ongoing consumption of the allergen, daily or near daily, with periodic follow-upEffectively indefinite
Long-term careContinued maintenance care offered; Latitude historically also offered Palforzia (now withdrawn) and Xolair alongside OITOngoing

Duration figures are Latitude's published numbers, checked September 2026.

The fine print

The daily rules, for the duration

None of this is Latitude-specific. It is what published OIT protocols generally require, because swallowing meaningful allergen doses safely demands it. The daily-life page compares these rules with the lighter sublingual ones.

  • Same time, every day The dose is taken daily, with food, at a consistent time. This continues through maintenance, which is to say indefinitely.
  • Rest windows No strenuous exercise or hot showers for roughly two to three hours after dosing; both can lower the reaction threshold. Latitude patients also mention avoiding strenuous activity and alcohol for several hours after a dose.
  • Illness holds Doses are held during fever or illness per clinic protocol, then resumed on the clinic's instructions.
  • Missed doses More than about three missed days means calling the clinic before resuming, because tolerance of the dose can slip quickly.
  • Adult cautions Alcohol around dosing is cautioned against for adults on published OIT protocols.

Geography and money

Where Latitude operates, and who pays

Latitude's FAQ says diagnostics and visits are typically covered in-network. The one-time OIT program fee is a non-covered service whose amount Latitude does not publish; patients report roughly $4,000 in the Bay Area and over $5,000 in New York. Payment plans are offered and the fee is FSA/HSA eligible.

RegionOfficesIn-network insurers, per Latitude's FAQ
Northern CaliforniaRedwood City, San Francisco, San Rafael (Marin), San RamonAetna, Anthem Blue Cross, Blue Shield, Cigna, Health Net, UnitedHealthcare, select HMOs
Southern CaliforniaPasadena, Irvine, San Diego, Sherman Oaks, West LAAetna, Blue Cross, Blue Shield, Cigna, Health Net, UnitedHealthcare
New York areaManhattan (Upper East Side), Brooklyn, Long Island, White PlainsAetna, Anthem, Empire Blue Cross, Cigna, Oxford, UnitedHealthcare

Insurer lists change; verify your specific plan with Latitude directly. Fee figures are patient-reported, shown as a range because reports conflict by region and time.

Outcomes

What Latitude publishes, and what it means

Latitude publishes outcome figures, which most clinics do not. They come from internal data, which deserves both credit and scrutiny.

of patients under 4 desensitized to their allergen(s) with OIT (internal data, 2026)
98%of patients under 4 desensitized to their allergen(s) with OIT (internal data, 2026)
of patients of all ages desensitized (internal data, 2026)
94%of patients of all ages desensitized (internal data, 2026)
of doses caused any reaction across 1,000+ OIT patients, overwhelmingly mild (AAAAI 2025, with Weill Cornell)
~5%of doses caused any reaction across 1,000+ OIT patients, overwhelmingly mild (AAAAI 2025, with Weill Cornell)
average time to maintenance, per Latitude
~8.4 moaverage time to maintenance, per Latitude

Earlier Latitude materials cited 92% desensitization within one year and 97% for under-4s, so treat the figures as a range across time and cohorts. Internal data is not peer review; ask any provider — ours included — who is in the denominator and what threshold counts as success.

The ledger

Strengths and constraints, side by side

What the record supports

Latitude's real advantages, stated first.

  • Supervised escalationEvery dose increase happens under clinicians, which is exactly when reaction risk peaks. The AAAAI 2025 figure of ~5% of doses causing any reaction, mostly mild, is a strong safety record for OIT at this scale.
  • SpeedMonths, not years, to maintenance: 6–12 published, about 8.4 on average. Under direct supervision, a clinic can escalate faster than any at-home protocol responsibly can.
  • Diagnosis firstOral food challenges are the gold standard, and patients credit Latitude's challenges with removing false-positive allergy labels entirely.
  • A clean third-party recordNo BBB complaints on file, 276 strongly positive Zocdoc reviews, 8.8/10 on Atly, and no petitions or organized skepticism anywhere we could find.
  • Academic tiesAffiliations with UCSF Benioff, Weill Cornell, and CHLA, and founders linked to the Stanford Sean Parker Center world.
What families weigh against it

The constraints, equally real.

  • GeographyAbout 12 offices, all in coastal California and greater New York. The FAST directory lists OIT clinics in 35 states; 15 states plus DC have none listed at all.
  • CadenceA clinic visit at the frequent cadence OIT up-dosing requires through the active phase. In one published study, 52% of patients offered peanut OIT declined it, and the top reason, at 28.5%, was time burden.
  • The non-covered fee$4,000 to over $5,000 by patient report, on top of covered visits, for a fee Latitude discloses as non-covered without publishing the amount.
  • OIT's side-effect profileIn the head-to-head peanut trial in children, OIT produced significantly more adverse reactions and withdrawals than sublingual immunotherapy — the price of its larger, faster threshold rise.
  • Rules for lifeMaintenance dosing continues indefinitely, with rest windows, illness holds, and timing discipline attached for the duration.

The trade

Speed versus gentleness, in the post-Palforzia landscape

The honest trade is speed versus gentleness. Under direct supervision, clinicians can treat more aggressively; in-clinic programs normally use OIT and accelerated protocols, sometimes adding a biologic such as Xolair so the patient can safely tolerate a significant dose of allergen. The biologic protects the patient during treatment; it is the immunotherapy that modifies the disease. Faster is not better for every patient, and neither is gentler.

Food SLIT is the gentler road. It uses much smaller, precise doses held under the tongue, typically 4 mg or less of protein per allergen per day; the effect comes through the sublingual mucosa, and swallowed, the same dose would be ineffective. Because the dose is smaller, food SLIT is generally safer, with fewer side effects: more gradual than OIT, sometimes slower, and easier to stay on. The head-to-head numbers say it plainly. In a randomized peanut trial in children, OIT raised reaction thresholds about 141-fold at 12 months versus about 22-fold for SLIT, and OIT produced significantly more adverse reactions and withdrawals. OIT buys depth and speed of desensitization; it pays in reactions and dropouts.

One more piece of context families should have: since Palforzia was withdrawn from the US market on July 31, 2026, no FDA-approved food immunotherapy exists. Every program in this market runs off-label, Latitude's included and ours included; off-label is not the same as unsafe, but it means no product label settles the protocol questions. Xolair is now the only FDA-approved food allergy medication, and it reduces reaction severity on accidental exposure rather than desensitizing. The treatment-options page maps the full landscape.

Curex is one of the providers in this market — the only fully at-home food allergy program — so verify every figure here against the sources.

The resolution

If the map or the math does not work

If you live within reach of the Bay Area, Los Angeles, San Diego, or greater New York offices, hold in-network insurance, and can sustain a clinic visit at the frequent cadence OIT up-dosing requires plus the $4,000–$5,000+ fee, your child may be a strong candidate for evaluation at Latitude, and nothing on this page argues otherwise. The program's speed and supervision are real, and its public record is clean.

Many American families do not fit that description. The FAST directory lists OIT clinics in 35 states, leaving 15 states plus DC with none listed; in the Midwest, the median distance to the nearest allergist is 57.3 miles. When 67 patients were offered commercial peanut OIT in a published study, 52% declined, with time burden the top reason at 28.5% and lifestyle modification second at 25%. Distance and cadence, not doubt about the science, are what keep families out of clinic OIT. The access page breaks this down state by state.

For those families the at-home route is the first door to try. Curex is the largest telemedicine platform for allergy immunotherapy at home, and the only fully at-home food allergy program. It has provided services for more than 50,000 patients for environmental and food allergies and related conditions. Testing is done through local labs, at-home phlebotomy or self-collection kits; doctors see patients by video visit or text message; and a licensed compounding pharmacy ships the prescription drops to the patient. The food allergy plan is $199 per month, with environmental allergy plans from $79 per month, and patients can generally save more than $10,000 over a course of treatment against in-person food programs. Food SLIT uses much smaller, more precise doses under the tongue. Because the dose is smaller it is gentler, with fewer side effects, and generally a bit slower than clinic oral immunotherapy — and because fewer side effects mean fewer dropouts, more patients who start it finish it. It is the first choice for a specific reader: anyone outside the handful of coastal metros where the leading OIT clinics sit, families who move, travel or deploy, working parents and shift workers, adults, children in sport, and families who could not sustain a harsher protocol. Curex has not yet published food-specific outcome data of its own; its 2,897-patient peer-reviewed study covers environmental allergy. The food program rests on the published peanut-SLIT trials cited here. In NIH-funded studies at UNC, 67–70% of children on extended peanut SLIT could tolerate 750–800 mg or more of peanut protein and a quarter to a third passed a full 5,000 mg challenge (PMID 31493887; PMID 36828080); in toddlers started at ages 1–4, the median tolerated dose after three years was 4,443 mg against 143 mg on placebo, 60% passed the challenge against none, and 48% showed remission after three months off treatment (PMID 37815782) — with no dose in any of the three studies requiring epinephrine. How Curex works covers the mechanics, and the clinic comparison puts the published figures side by side.

The third door is the in-person sublingual clinic, and it is the named option for the patient who must be seen in person first. Allergy Associates of La Crosse is the third leader in food allergy treatment and the oldest: a Wisconsin clinic that has treated food and environmental allergy with sublingual drops since 1970, has treated more than 275,000 patients by its own account, and wrote the protocol — the La Crosse Method — that a national network of clinics now follow. Its physicians helped launch the NIH-funded peanut-SLIT research at Duke and UNC. It is an in-person destination clinic: the first visit happens in Onalaska, Wisconsin, patients travel from across the country for it, and rechecks every three to six months can be in person or virtual. It treats infants through adults, explicitly including patients with a history of anaphylaxis or uncontrolled asthma; the first visit runs $750–850 ($1,000–1,400 complex), food drops about $2.20 a day patient-pay, over 3–5 years. Same treatment as the at-home route; two ways in.

Where that leaves you

The practical next step

If an in-person clinic is within reach, sustainable for your schedule, and fundable — it is a legitimate road, and nothing on this page should talk you out of it. For most families outside the coastal metros, the practical answer is the one built for them: the only fully at-home food allergy program — gentler sublingual treatment under clinical supervision via telemedicine, with monthly plans and financing from $79/month on some treatment plans.

See if you may be a candidateOr compare all three providers first

❓Frequently Asked Questions

Latitude publishes 6 to 12 months of active treatment to reach maintenance, with an average of about 8.4 months. During that phase, dose escalations happen in clinic at the frequent cadence OIT up-dosing requires, with daily home dosing in between. Reaching maintenance is not the end: regular dosing of the allergen continues indefinitely, because the desensitization is maintained by the ongoing exposure, and Latitude offers long-term maintenance care for exactly that reason. That last part is standard across food immunotherapy in every program, ours included.

Latitude's own FAQ says diagnostics and visits are typically covered when you are in-network, and it lists major insurers in each region, including Aetna, Cigna, UnitedHealthcare, and the regional Blue plans. The one-time OIT program fee is different: Latitude calls it a non-covered service and does not publish the amount. Patients report roughly $4,000 in the Bay Area and over $5,000 in New York, so treat it as a $4,000–$5,000+ range that varies by region and time. Payment plans exist and the fee is FSA/HSA eligible. One Bay Area patient called the fee shocking to discover despite having done plenty of research on coverage beforehand, so ask for the full figure in writing before you commit.

As of 2026, Latitude publishes that 98% of patients under 4 achieved desensitization to their allergen(s) with oral immunotherapy, and 94% of patients of all ages did, sourced to internal data. Earlier materials cited 92% within one year and 97% for under-4s, so read the figures as a range across time and cohorts. On safety, an AAAAI 2025 analysis with Weill Cornell found about 5% of doses among 1,000+ OIT patients caused any reaction, the overwhelming majority mild. Internal data is not peer review, so it deserves both credit and scrutiny — the same questions apply to every provider's figures, ours included.

The published shape across OIT programs: dose at a consistent time each day with food; avoid strenuous exercise and hot showers for roughly two to three hours after dosing, since both can lower the reaction threshold; hold doses during fever or illness per clinic protocol; call the clinic before resuming after about three missed days; and observe alcohol cautions as an adult. Latitude patients likewise mention avoiding strenuous activity and alcohol for several hours after a dose. None of this is Latitude-specific. It is what swallowing meaningful allergen doses safely requires, and [the daily-life comparison](/learn/food-immunotherapy-daily-life) sets it against the lighter sublingual rules.

Adults are case by case. One public account describes a 36-year-old accepted for peanut OIT even though, in the patient's words, the clinic stated they don't normally treat adults; that patient cited a peanut component IgE of 2.0 or greater as the threshold discussed, and reached maintenance in the standard 6–12 months. Public threads also show demand for less common allergens, including a shrimp OIT inquiry that found no reviews to read. Both are ask-the-clinic questions; neither has a published policy we could verify.

Remarkably little, by the standards of this market. Latitude's BBB profile is Not Rated with no complaints on file, its New York Zocdoc page carries 276 strongly positive reviews, and no petition or organized skepticism cluster exists in public forums, which is a genuine contrast with some peers (see [the clinic comparison](/learn/food-allergy-clinics-compared)). The recurring negative is money: an Atly reviewer wrote that the program fee is over $5,000, which may be cost prohibitive. One reviewer also reported being told to stop antihistamines before a virtual visit without advance warning. That is the extent of the negative public record we could verify.

Candidacy is clinical, so the honest answer is that your child may be a candidate, and only an evaluation can say. A history of anaphylaxis or severe, poorly controlled asthma routes to in-person assessment regardless of which provider you choose — Allergy Associates of La Crosse is one clinic that explicitly treats those patients in person, with sublingual drops. Beyond that, the fit question is practical: Latitude's model favors families within reach of its California or New York offices who can sustain visits at the frequent cadence OIT up-dosing requires and absorb a $4,000–$5,000+ non-covered fee. Families outside those metros, families who move or travel, working parents, adults, children in sport, and families who want a gentler side-effect profile may be candidates for at-home sublingual treatment through Curex — the only fully at-home program, in every state, at $199 per month. Oral food challenges happen in a clinic on every path, including for Curex patients.

Latitude's roughly 12 offices sit entirely in coastal California and greater New York, and OIT elsewhere is thinner than most families expect: the FAST directory lists OIT clinics in 35 states, meaning 15 states plus DC have none listed at all, and a Midwest study put the median distance to the nearest allergist at 57.3 miles. The cadence compounds the distance; in one published study, 52% of patients offered commercial peanut OIT declined it, with time burden the top reason at 28.5%. [The access page](/learn/no-oit-clinic-near-me) maps the geography state by state. Curex is the only fully at-home food allergy program: testing through local labs or kits, doctors by video visit or text, prescription drops shipped by a licensed compounding pharmacy — every state, from age 2, $199 per month, gentler doses that more patients finish; food challenges still happen in a clinic when indicated. Allergy Associates of La Crosse offers the same sublingual treatment in person, with one first visit in Onalaska, Wisconsin, and rechecks that can be virtual.

If you experience sudden difficulty breathing, throat swelling, or other signs of anaphylaxis, call 911. A prescribed epinephrine auto-injector is the first-line treatment — not antihistamines.

This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. Content reviewed by board-certified allergists at Curex.

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