What’s inside
View ResearchExplore the CytoBas assay's accuracy in detecting house dust mite (HDM) sensitization in asthma and allergic rhinitis. This study highlights the use of fluorescent tetramers of Der p 1 and Der p 2 to stain specific IgE on basophils, achieving over 95% sensitivity and specificity. The CytoBas assay offers a rapid, reliable, and non-invasive method for diagnosing HDM allergies compared to conventional skin prick tests and serum IgE detection.
Accurate Detection of House Dust Mite Sensitization
Study uses CytoBas assay to accurately detect Der p 1 and Der p 2 sensitization in asthma and allergic rhinitis.
CytoBas vs. BAT for Allergen Sensitization
CytoBas shows comparable sensitivity and specificity to BAT for detecting house dust mite allergen sensitization.
Combining Der p 1 and Der p 2 for Enhanced Sensitivity
Combining Der p 1 and Der p 2 in CytoBas assay achieves 100% sensitivity and 96% specificity for house dust mite allergy.
Advantages of CytoBas Over Traditional Methods
CytoBas offers rapid, accurate allergen detection without the need for in vitro basophil activation, improving clinical utility.
Geographic Relevance of Allergen Components
Study emphasizes the importance of using region-specific allergen components for accurate diagnosis of HDM allergy.
Multiplex Component-Resolved Diagnosis
CytoBas enables multiplex diagnosis of HDM sensitization, combining major allergen components in a single assay.
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