Allergy Immunotherapy Researches & Insights
Our teams constantly curate the best researches on Allergy Immunotherapy around the world and bring it to you.
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CytoBas: Accurate Allergy Testing for Asthma & Rhinitis with 95% Success
CytoBas offers precise allergy testing for asthma & rhinitis with 95% success. Discover how CytoBas accurately detects house dust mite sensitization using Der p 1 and Der p 2 on basophils, achieving over 95% sensitivity and specificity, providing a rapid, non-invasive alternative to traditional tests.
View ResearchUncovering IgE-Fated B Cell Memory: New Insights for Allergy Therapy
Discover groundbreaking insights into IgE-fated B cell memory and its role in allergy immunotherapy. This study unveils the plasticity of pathogenic IgE responses and explores how blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells, offering new strategies for lifelong allergy treatment.
View ResearchGenetic Links Between Celiac Disease & Type 2 Inflammatory Diseases Unveiled
Discover the genetic connections between celiac disease and type 2 inflammatory diseases like atopic dermatitis, asthma, and allergic rhinitis. This study uses Mendelian Randomization to reveal significant associations, offering insights into inflammatory responses and potential management strategies.
View ResearchOrigins and Diversity of Bone Marrow Plasma Cells in Food Allergies
Discover the origins and diversity of pan-isotype human bone marrow plasma cells in food allergies. This study uncovers unique IgM, IgG, IgA, and IgE properties in allergic and non-allergic individuals using advanced RNA and CITE-seq analysis, highlighting bone marrow's role in peanut allergy.
View ResearchTracking Allergy Trends: Wastewater Reveals Pollinosis Impact in Zurich
Explore Zurich's allergy trends with innovative wastewater analysis. Learn how studying antihistamine markers in wastewater reveals pollinosis impacts and day-to-day variations in allergy symptom burden. Discover the potential of WBE for cost-effective, objective allergy monitoring.
View ResearchMRI & AI Decode Molecular Biology and Outcomes in Pediatric Brain Tumors
Explore how multiparametric MRI and AI decode molecular biology and treatment outcomes in pediatric low-grade glioma. Learn about a comprehensive radiogenomic analysis that identifies immunological clusters, predicts prognosis, and enhances precision medicine for better treatment response.
View ResearchAtopy Boosts Survival & Cuts Brain Metastasis Risk in Cutaneous Melanoma
Explore how atopy boosts survival and reduces brain metastasis risk in cutaneous melanoma. This study shows elderly individuals with atopic dermatitis have better survival rates and lower brain metastasis risks. Atopy may enhance immune responses, providing protection against melanoma progression.
View ResearchImmunotherapy Breakthrough: Immunoediting Map of Human Cancers Unveiled
Immunotherapy Breakthrough: Discover the unveiling of an immunoediting map of human cancers through single-cell deconvolution. This study reveals crucial changes in immune cell types between tumors and healthy tissues, highlighting increased mast cells and decreased NK cells, paving the way for novel cancer immunotherapies.
View ResearchUnveiling Dietary Antigens in Oral Tolerance: Allergy Immunotherapy Insights
Explore groundbreaking research on dietary antigens in oral tolerance. Uncover key T cell receptors responding to maize, wheat, and soy proteins, essential for Treg development in the intestine. Insights reveal mechanisms that could revolutionize allergy immunotherapy and prevention strategies.
View ResearchDupilumab Reduces Type 2 Response in N-ERD During ASA Challenge
Explore how dupilumab reduces the type 2 response in N-ERD patients during ASA challenges. This study examines nasal mediators and transcriptomic profiles before and after 24 weeks of therapy, showing reduced type 2 cytokines. Discover the potential of dupilumab in managing ASA-induced reactions.
View ResearchUnlocking Osteosarcoma: Immunosuppressive Tumor Insights & Therapy Needs
Unlock the complexities of osteosarcoma with insights into its immunosuppressive microenvironment. Explore single-cell RNA sequencing and spatial transcriptomics that reveal interactions of MDSCs and exhausted T-cells, emphasizing the urgent need for innovative immunotherapy approaches.
View Research"Boosting Lung Cancer Survival: NK and CD8 T Cells' Combined Impact"
Discover how the combined impact of NK and CD8 T cells boosts survival in non-small cell lung cancer despite MHC class I loss. This study highlights the benefits of high densities and spatial colocalization of these cells, suggesting potential for combined immunotherapies to enhance anti-tumor immunity.
View ResearchSeasonal Antihistamine Use Linked to Lower Ovarian Cancer Risk: CLOCS Study
Seasonal antihistamine use linked to lower ovarian cancer risk, according to the CLOCS study. This observational case-control research found that spring and summer antihistamine purchases significantly reduced ovarian cancer risk, especially non-serous types. No effect observed for year-round use.
View ResearchCFTR's Role in Food Allergen Tolerance: Insights from Mice and Humans
Explore CFTR's role in food allergen tolerance in mice and humans. Discover how individuals with cystic fibrosis develop IgG4 antibodies to peanut allergens without allergies, revealing unique immune responses. Unveil potential therapeutic strategies for food allergies.
View ResearchEvaluating Epitope Prediction Tools for Allergens: Fel d 1 Case Study
Discover the effectiveness of computational epitope prediction tools for allergens like Fel d 1. Benchmarking IEDB methods reveals limitations in identifying B-cell and T-cell epitopes, highlighting the need for improved accuracy in allergen research and immunotherapy development.
View ResearchBoost Food Tolerance: Expand Antigen-Specific Memory Cells to Fight Allergies
Boost food tolerance & fight allergies! Discover how expanding antigen-specific memory cells can aid in food tolerance induction. Learn about the promising hybrid diet approach that reduces inflammation and enhances mucosal recovery in peanut allergy. Explore allergy immunotherapy today!
View Research0.005% Tacrolimus Drops Ease Allergy Symptoms in 8 Days: Study Highlights
Discover how 0.005% Tacrolimus Drops reduce allergy symptoms in just 8 days. A randomized, placebo-controlled trial reveals significant relief from allergic rhinoconjunctivitis symptoms like redness, itching, and sneezing. Learn about the safety and efficacy of Tacrosolv for managing allergic eye diseases.
View ResearchAI Predicts IgE Levels in Allergic Rhinitis Patients on Immunotherapy
Discover how AI predicts IgE levels in allergic rhinitis patients on immunotherapy, enhancing diagnosis and treatment. This study leverages machine learning and decision trees to forecast IgE concentrations, improving personalized allergy care and clinical outcomes.
View ResearchOptimal Timeframe for Donating High-Antibody COVID-19 Plasma
Explore the optimal timeframe for donating high-antibody COVID-19 plasma. Learn how SARS-CoV-2 IgM, IgG, and neutralization responses persist for 100 days, with the best donation period within the first 60 days. Enhance convalescent plasma therapy with refined donor selection criteria.
View ResearchCOVID-19 Severity in MS Patients on Immunotherapy: Key Insights from Global Data
Discover vital insights on how COVID-19 symptoms impact MS patients on immunotherapy, based on the COVID-19 in MS Global Data Sharing Initiative. Learn how comorbidities like hypertension and chronic kidney disease influence outcomes, while MS type and disease-modifying therapies show no significant effect.
View ResearchChemotherapy Enhances Immunotherapy in Secondary Tumors: Study Insights
Discover how chemotherapy boosts immunotherapy in secondary tumors. This study highlights that tumor-draining lymph nodes are crucial only in early stages, while sequential 5-FU and immunotherapy significantly improves outcomes, offering an optimized treatment strategy for advanced cases.
View ResearchAntigen Uptake in Mice: Sublingual Immunotherapy With Beads Study
Explore the morphofunctional analysis of antigen uptake in mice following sublingual immunotherapy with beads. Discover significant findings in sublingual mucosa regions, highlighting sex-related differences in bead accumulation, and potential impacts on SLIT efficacy.
View ResearchAllergy Immunotherapy: Blocking IL-4Ra to Avert Anaphylaxis
Explore how blocking IL-4Ra can reprogram allergic responses and prevent anaphylaxis. This study reveals that disrupting IL-4/IL-13 signaling halts IgE production, offering new hope for treating food allergies and severe allergic reactions. Discover innovative therapies in allergy immunotherapy.
View ResearchRevolutionary Peanut Allergy Test: 93% Accurate Epitope Mapping Method
Discover the revolutionary Peanut Allergy Test with 93% accuracy using Epitope Mapping. The Bead-Based Epitope Assay (BBEA) outperforms traditional methods, validated across multiple cohorts, offering a reliable, non-invasive diagnosis for better patient outcomes and clinical practices.
View ResearchESCAPE Trial: Personalized Immunotherapy for Severe COVID-19 Patients
Discover the ESCAPE trial: a phase II study on personalized immunotherapy for critically ill COVID-19 patients. Anakinra showed promise in reducing organ dysfunction, especially in those with macrophage activation syndrome or complex immune dysregulation. Explore key findings and clinical benefits.
View ResearchBoosting Cancer Immunity: Low-Dose CDK4/6 Inhibitors as Potential Allies
Discover how low-dose CDK4/6 inhibitors like Abemaciclib and Palbociclib can enhance breast cancer immunotherapy by inducing pathway-specific MHC class I ligands. Learn about their potential to synergize with T cell-based treatments, opening new doors for targeted cancer therapies.
View ResearchPeanut OIT Suppresses Specific T Helper Cells, Study Reveals Insights
Discover how peanut oral immunotherapy (OIT) suppresses distinct T helper cell subsets. This study leverages single-cell RNA and TCR sequencing to reveal suppression of Th2 and Th1 signatures in peanut-reactive T cells, offering fresh insights into the immunological mechanisms behind OIT outcomes.
View ResearchMicrobial Stimuli Guide Immune Cells to Target Organs for Effective Treatment
Discover how microbial stimuli guide immune cells to target organs for effective treatment. This groundbreaking study reveals how subcutaneously delivered microbial-based therapies recruit immune effector cells to diseased organs, offering new hope for treating cancer, infections, and chronic inflammatory disorders.
View ResearchAI in Allergy Treatments: Common Targets for Asthma, Eczema, Food Allergy
Discover how AI is revolutionizing allergy treatments. Learn how the PandaOmics platform uncovers key targets like IL5, PTAFR, and RNF19B for asthma, eczema, and food allergies. Explore the potential of AI in accelerating drug discovery and creating effective multi-allergy therapies.
View ResearchPromising CAR/CXCR5-T Cell Therapy Shows Hope for SIV Remission
Discover the promise of CAR/CXCR5-T cell therapy for SIV remission in rhesus macaques. This breakthrough approach modifies T cells to target viral RNA+ cells in lymphoid follicles, showing potential for future HIV treatments. Safe, effective, and innovative in reducing viral loads.
View ResearchAdaptive-to-Innate Immune Ratio: Key to Better Immunotherapy Outcomes
Discover how the adaptive-to-innate immune ratio (A/I ratio) impacts cancer prognosis and immunotherapy success. This study reveals that a higher A/I ratio correlates with improved survival, better treatment outcomes, and significant gender differences, suggesting its potential as a biomarker for personalized care.
View ResearchBasophil & B-Cell Biomarkers: Key in Food Allergy & Immunotherapy Tracking
Discover how Basophil and B-cell biomarkers, like CD63, CD203c, and CD73, are crucial for tracking disease activity in food allergies and oral immunotherapy. This study underscores their potential in monitoring and managing peanut allergy desensitization and long-term tolerance.
View ResearchRare IgE+ Memory B Cells in Food Allergy: Study Questions Their Role
Explore a groundbreaking study on the rarity and role of IgE+ memory B cells in food allergy. Using advanced single-cell analysis, researchers challenge their clinical utility and suggest IgE recall responses may come from non-IgE MBCs. Dive into this transformative allergy immunotherapy research.
View ResearchAtopic Skin Barrier Issues Fuel Malassezia Yeast Growth: New Study Insights
Discover how atopic skin barrier issues contribute to Malassezia yeast overgrowth. This new study reveals that compromised epidermal barriers in atopic dermatitis make conditions ideal for Malassezia, shedding light on the role of skin microbiota in common barrier disorders.
View ResearchAntibody Landscape: C57BL/6 Mice Cured of B78 Melanoma by Immunotherapy
Discover the antibody landscape in C57BL/6 mice cured of B78 melanoma via immunotherapy. Our study uses whole-proteome peptide arrays to reveal a diverse antibody repertoire, highlighting immune memory's specificity and potential to boost cancer immunotherapy effectiveness. Read more.
View Research18-Year Study Shows Long-Term Benefits of Grass, Birch, Mugwort AIT
Discover the 18-year benefits of grass, birch, and mugwort allergen immunotherapy (AIT) from a national cohort study in Denmark. Analysis of 7,914 patients shows significant reduction in anti-allergic nasal spray use within the first 5 years, with lasting effects, enhancing allergy management and quality of life.
View ResearchOral Insulin Therapy for Kids at Risk for Type 1 Diabetes: Study Insights
Explore the Pre-POInT-early study on oral insulin therapy for kids at risk for type 1 diabetes. This randomized trial reveals that oral insulin is well-tolerated, modifies immune responses in genetically predisposed infants, and interacts with the gut microbiome. Learn about its safety and efficacy.
View ResearchCOVID-19 Outcomes in Allergic Rhinitis Patients on Allergen Immunotherapy
Discover how allergen-specific immunotherapy (AIT) affects COVID-19 outcomes in allergic rhinitis patients. Compare infection rates, hospitalization, and pneumonia between those on AIT and those not. Findings show AIT doesn't increase SARS-CoV-2 risk, with females possibly less susceptible.
View ResearchCarrageenan Nasal Spray Shows Relief for Grass Pollen Allergy Symptoms
Discover how a carrageenan-containing nasal spray, Callergin, provides relief for grass pollen allergy symptoms. A recent randomized, controlled trial shows significant reduction in rhinorrhea and nasal congestion, highlighting the spray's effectiveness. Learn more about this promising treatment.
View ResearchDiscover Genes Enhancing Immunotherapy in Lymphomas Through CRISPR Screening
Discover genes enhancing lymphoma immunotherapy through CRISPR screening. Learn how genome-wide screens identify tumor-specific regulators of MHC-I and MHC-II immunosurveillance, uncovering potential therapeutic targets like SUGT1 and inhibitors of EZH2 for advanced cancer treatment.
View ResearchUnlocking Peanut Allergy: Key Genes & Pathways Revealed by RNAseq Study
Unlock the molecular dynamics of peanut allergy with a groundbreaking RNAseq study. Discover key genes and pathways like IL-17 signaling and cytokine interactions. Unveil potential therapeutic targets and biomarkers for better allergy management.
View ResearchKey Inflammation Markers for Outgrowing Cow's Milk Allergy Revealed
Discover key inflammation markers for outgrowing cow's milk allergy. This study, using the Olink® Target 96 Inflammation panel, analyzes infant saliva, uncovering TNF signaling and cytokine pathways critical in CMA resolution. Learn about the distinctions in immune markers between resolved and persistent cases.
View ResearchNew Intranasal Vaccine Boosts Tuberculosis Treatment Efficacy
Discover how a novel intranasal stringent response vaccine targeting dendritic cells enhances tuberculosis treatment. This adjunctive therapy boosts Th1/Th17 responses and improves mycobactericidal activity, significantly reducing lung bacterial burden in a murine TB model.
View ResearchPKC Delta's Role in Cancer: Boosting Immunotherapy Effectiveness
Explore how Protein Kinase C Delta (PKCδ) regulates mononuclear phagocytes and impacts cancer immunotherapy. Learn how PKCδ deficiency boosts anti-PD-1 therapy efficacy by reprogramming phagocytes and optimizing T cell activation, presenting a novel strategy for improving cancer treatment outcomes.
View ResearchCAR-T Breakthrough: AML-Specific Integrin-β2 Identified as Therapy Target
Discover the CAR-T breakthrough targeting AML-specific integrin-β2, identified through structural surfaceomics. This promising approach shows CAR-T cells can eliminate AML cells without harming normal ones, offering a new hope in immunotherapy with minimal toxicity.
View ResearchInnovative Allergy Immunotherapy: PEGylated Peptides Prevent EAE
Explore how PEGylated antigenic peptides prevent experimental autoimmune encephalomyelitis (EAE), a model for MS, by enhancing vaccine efficacy, inducing regulatory T cells, and reducing CNS immune cell infiltration. Learn about their potential for safer, effective autoimmune disease therapies.
View ResearchBoosted CAR-T Therapy: Enhanced Tumor Clearance with New Signaling Motifs
Discover the power of boosted CAR-T therapy with new signaling motifs. Learn how the development of Chimeric Adapter Proteins (CAPs) enhances anti-tumor efficacy, extends tumor clearance, and addresses CAR-T cell limitations like cytokine secretion and exhaustion in leukemia models.
View ResearchBoosting Peptide Immunotherapy: SAgAs Enhance Safety and Fight Autoimmune Diabetes
Boost peptide immunotherapy for autoimmune diabetes with SAgAs! Learn how soluble antigen arrays outperform free peptides, boosting safety, regulatory T cells, and minimizing anaphylaxis risks in NOD mice. Discover promising advancements in autoimmune and allergy therapies.
View ResearchBoosting Anti-EGFR CAR T Therapy for Glioblastoma with CD47 Blocker
Discover advanced anti-EGFRvIII CAR T cell therapy for glioblastoma, enhanced by a SIRPγ-derived CD47 blocker. This innovation surmounts the tumor's immunosuppressive microenvironment, showing remarkable tumor eradication and prolonged survival in studies, outperforming traditional therapies.
View ResearchAIRE Checkpoint in B Cells: New Insights for Allergy Immunotherapy
Explore groundbreaking research on AIRE in B cells, revealing its role in limiting antibody diversification. Understand its impact on T cell tolerance, antibody affinity maturation, and class switching, highlighting potential advancements in allergy immunotherapy and autoimmunity prevention.
View ResearchRituximab Biosimilars: Breakthrough in B Cell Autoimmune Disease Treatment
Discover the potential of rituximab biosimilars for treating B cell-mediated autoimmune diseases. Our study highlights its success in 116 conditions, originally approved for lymphoma. Explore rituximab's efficacy in targeting CD20+ B cells and promising future in autoimmune therapy.
View ResearchWe Treat Indoor & Outdoor Allergies
Weed Pollens
Dust Mites
Molds
Tree Pollens
Cat Allergies
Dog Allergies
Weed Pollens
Dust Mites
Molds
Tree Pollens
Cat Allergies
Dog Allergies
Currently, we do not offer treatment for food allergies. However, we are working on providing this service soon. Be the first to know when it’s available.
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Get Started in 3 Simple Steps
1
Take quiz and sign up for an at-home or in-lab allergy test
Consult with Curex clinician online
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Insurance covers clinical consultations.
Subscription fee ($49/month not billed to insurance) covers immunotherapy, shipping & related costs.
At-home Immunotherapy
Avoid the Shots, Just Try Curex!
The Better Alternative to Allergy Shots
Curex
$49/month
+copay
Allergy Shots
$1,500-$4,000
per year
per year
Lauren S.
No longer having to go the doctor's office a few times a week for painful shots.
Tony P.
I have done allergy shots in the past but found it pretty inconvenient to go every week. I really like the ease as compared with physically going to the doctors office.
Robert S.
The treatment is much less expensive than a course of allergy shots at a doctor's office and eliminates numerous trips to the doctor's and all the waiting time.
Janie L.
My seasonal allergies were much less severe than years prior. Most importantly, the convenience of taking drops in my own home is unbeatable.
Lauren S.
No longer having to go the doctor's office a few times a week for painful shots.
Tony P.
I have done allergy shots in the past but found it pretty inconvenient to go every week. I really like the ease as compared with physically going to the doctors office.
Robert S.
The treatment is much less expensive than a course of allergy shots at a doctor's office and eliminates numerous trips to the doctor's and all the waiting time.
Janie L.
My seasonal allergies were much less severe than years prior. Most importantly, the convenience of taking drops in my own home is unbeatable.
So safe you can do it from home!
Sublingual immunotherapy offers superior safety
.webp) | | |
|---|---|---|
| Sublingual immunotherapy | Allergy Shots | |
| Gentle Build-up |  |  |
| Rate of Severe Reaction | <0.03% | <1% |
| Millions of Users | | |
| EpiPen Prescribed | | |
| Post Use Waiting Period | Not necessary | 30 mins |
| Safe for Home Use | | |
Studies have shown a significantly lower risk for anaphylaxis relative to allergy shots, allowing you to take them in the comfort of your own home.
"Immunotherapy can be amazing"
FAQs
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Is sublingual immunotherapy safe?
