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Written and prepared by:
Airton Pereira e Silva, Bárbara Oliveira Marmello, Ana Letícia Bentes, Claudia Regina Josetti das Neves Faccini, Sónia Kristy Pinto Melo Rodrigues, João Ricardo Almeida Soares, Sylvia Maria Nicolau Campos, Gerlinde Agate Platais Brasil Teixeira
Explore the potential of expanding antigen-specific memory cells to boost food tolerance induction. This study investigates whether an antigen-specific tolerogenic bystander effect can enhance the recovery of inflamed intestinal mucosa in a mouse model of peanut allergy. Findings indicate that a hybrid diet containing both tolerogenic and allergenic components can ameliorate local inflammation, increase regulatory T cells, and promote mucosal recovery.
Study evaluates how expanding antigen-specific memory cells can boost food tolerance and aid recovery from intestinal inflammation.
Research investigates oral tolerance mechanisms and the role of memory cells in recovering from peanut-induced gut inflammation.
Examining the immune cell profiles and antibody levels in mice to understand gut inflammation and oral tolerance in peanut allergy.
Study shows a hybrid diet with peanuts increases regulatory T cells and memory B cells, improving mucosal recovery in peanut-allergic mice.
Detailed histological evaluation reveals how different diets affect intestinal inflammation and recovery in peanut-allergic mice.
Research highlights the role of CD4+CD25+Foxp3+ regulatory T cells in enhancing oral tolerance and reducing gut inflammation in food allergy.
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