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View ResearchExplore the potential of expanding antigen-specific memory cells to boost food tolerance induction. This study investigates whether an antigen-specific tolerogenic bystander effect can enhance the recovery of inflamed intestinal mucosa in a mouse model of peanut allergy. Findings indicate that a hybrid diet containing both tolerogenic and allergenic components can ameliorate local inflammation, increase regulatory T cells, and promote mucosal recovery.
Inducing Food Tolerance with Antigen-Specific Memory Cells
Study evaluates how expanding antigen-specific memory cells can boost food tolerance and aid recovery from intestinal inflammation.
Mechanisms of Oral Tolerance in Peanut Allergy
Research investigates oral tolerance mechanisms and the role of memory cells in recovering from peanut-induced gut inflammation.
Immune Response in Intestinal Inflammation
Examining the immune cell profiles and antibody levels in mice to understand gut inflammation and oral tolerance in peanut allergy.
Impact of Hybrid Diet on Peanut Allergy
Study shows a hybrid diet with peanuts increases regulatory T cells and memory B cells, improving mucosal recovery in peanut-allergic mice.
Histopathological Analysis of Intestinal Mucosa
Detailed histological evaluation reveals how different diets affect intestinal inflammation and recovery in peanut-allergic mice.
Regulatory T Cells in Food Allergy Treatment
Research highlights the role of CD4+CD25+Foxp3+ regulatory T cells in enhancing oral tolerance and reducing gut inflammation in food allergy.