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Fluticasone/vilanterol (Breo Ellipta) Overview: Benefits, Side Effects | Curex

Explore the latest in allergy relief with our review of Fluticasone/vilanterol (Breo Ellipta). We cover its effectiveness, side effects, and how it compares to other treatments. Perfect for those seeking a comprehensive overview in a concise format.
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Fluticasone/vilanterol (Breo Ellipta) Overview: Category & Primary Use

 

Overview of Fluticasone/Vilanterol (Breo Ellipta)

 

Fluticasone/vilanterol, marketed under the brand name Breo Ellipta, is a combination medication used in the management of respiratory disorders. It is formulated as a dry powder inhaler and combines two active ingredients: Fluticasone furoate, a corticosteroid, and Vilanterol, a long-acting beta-agonist (LABA).

 

Drug Category

 

  • Fluticasone furoate is classified as a steroid medication specifically acting as a glucocorticoid receptor agonist.
  • Vilanterol is a long-acting beta-agonist that functions as a bronchodilator, helping to relieve respiratory symptoms.

 

Indications and Usage

 

Breo Ellipta is primarily prescribed for the long-term, once-daily maintenance treatment of specific respiratory conditions. It helps in reducing inflammation and widening the airways in the lungs, allowing for easier breathing and improving overall lung function.

 

  • Asthma: It is used for the management of asthma in adults and children over a certain age, typically aimed at improving symptoms and reducing the frequency of exacerbations.
  • Chronic Obstructive Pulmonary Disease (COPD): This medication is also indicated for COPD, including conditions such as chronic bronchitis and emphysema, to improve symptoms and prevent flare-ups.

 

Mechanism of Action

 

The combination of fluticasone and vilanterol in Breo Ellipta works synergistically to manage respiratory conditions:

 

  • Fluticasone Furoate: As a corticosteroid, it reduces inflammation in the lungs, thus cutting down the swelling and irritation of the airways. This facilitates smoother airflow and eases breathing difficulties.
  • Vilanterol: It acts on the beta-2 adrenergic receptors in the lungs, promoting relaxation and dilation of the bronchial tubes. This bronchodilatory effect contributes to a decrease in airway resistance and enhances airflow.

 

Conclusion

 

Fluticasone/vilanterol (Breo Ellipta) is a potent therapeutic option for individuals with asthma and COPD, providing synergistic effects through its dual-action components. By targeting both inflammation and bronchoconstriction, it aids in better symptom control and enhances quality of life for those suffering from ongoing respiratory disorders.

 

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What Conditions Does Fluticasone/vilanterol (Breo Ellipta) Treat?

 

Fluticasone/vilanterol, commercially known as Breo Ellipta, is a medication used to manage and treat certain respiratory conditions. This combination therapy involves fluticasone, an inhaled corticosteroid that reduces inflammation, and vilanterol, a long-acting beta-agonist that helps in relaxing bronchial muscles.

 

Chronic Obstructive Pulmonary Disease (COPD)

 

  • Fluticasone/vilanterol is prescribed for the maintenance treatment of chronic obstructive pulmonary disease (COPD). This includes chronic bronchitis and emphysema.
  • The medication works by reducing flare-ups and lowering the frequency of exacerbations in COPD patients.
  • It helps improve lung function by relaxing muscles around the airways, leading to easier breathing over time.

 

Asthma

 

  • Breo Ellipta is also utilized as a once-daily maintenance treatment for asthma in individuals who require a combination of inhaled corticosteroid and long-acting beta-agonist (LABA), specifically when asthma is not adequately controlled with an inhaled corticosteroid alone.
  • It helps in achieving better control over asthma symptoms by preventing inflammation and maintaining open airways.
  • Regular use can significantly decrease the risk of severe asthma attacks by stabilizing the condition.

 

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Fluticasone/vilanterol (Breo Ellipta): Effectiveness and Advantages Overview

 

Fluticasone/vilanterol (Breo Ellipta) is a combination medication used primarily for managing chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). It offers multiple benefits that enhance both lung function and overall quality of life.

 

Improved Lung Function

 

  • The combination of fluticasone and vilanterol works synergistically to open the airways, leading to better airflow and increased lung capacity.
  • Regular use can result in a noticeable improvement in breathing comfort and reduced shortness of breath.

 

Reduced Frequency of Exacerbations

 

  • This medication helps in keeping asthma attacks and COPD exacerbations at bay, significantly reducing their occurrence.
  • It provides long-term control over symptoms, thanks to its anti-inflammatory and bronchodilator properties.

 

Convenience and Compliance

 

  • Breo Ellipta is administered once daily, offering ease and convenience, which improves medication adherence among patients.
  • The user-friendly inhaler design ensures proper dosing and lessens the room for user error.

 

Enhancement of Quality of Life

 

  • By maintaining open airways and mitigating symptoms, users frequently experience an overall improvement in quality of life, enabling more activity and less discomfort.
  • Effective symptom management leads to fewer disruptions in daily activities and enhances the ability to maintain a normal lifestyle.

 

Comprehensive Therapeutic Action

 

  • Fluticasone acts as a potent anti-inflammatory corticosteroid, reducing airway inflammation.
  • Vilanterol serves as a long-acting beta agonist that relaxes muscles within the airways, complementing fluticasone's effects.

 

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Fluticasone/vilanterol (Breo Ellipta) Side Effects: Common and Serious, When to Seek Help

 

Side Effects of Fluticasone/Vilanterol (Breo Ellipta)

 

  • Common Side Effects: Patients may experience headaches, throat irritation, cough, or a hoarse voice.
  • Serious Side Effects: Potential serious side effects include heart palpitations, high blood pressure, signs of infection (such as fever or sore throat), and an increase in asthma-related symptoms.
  • Allergic Reactions: Some people may experience an allergic reaction, which can include symptoms such as rash, itching, swelling of the face, lips, or throat, severe dizziness, and trouble breathing.

 

Safety Precautions When Using Fluticasone/Vilanterol

 

  • Prescribed Usage: Use Breo Ellipta exactly as prescribed by a healthcare professional. Do not increase your dose or frequency without consulting your doctor.
  • Medical History: Inform your healthcare provider about your complete medical history, especially if you have heart disease, high blood pressure, seizures, thyroid problems, diabetes, bone loss, eye problems, or liver disease.
  • Monitor Symptoms: Regularly monitor your symptoms, and seek immediate medical attention if you notice a worsening of respiratory symptoms or if you do not feel any relief after using the inhaler.
  • Exposure to Infections: As corticosteroids can weaken the immune system, avoid being around people who are sick or have infections. Consult your physician if you have been exposed to chickenpox or measles.
  • Regular Check-Ups: Schedule regular check-ups with your doctor to effectively monitor and manage any side effects or complications.

 

A safer solution to allergies: try immunotherapy today!

Advantages of Immunotherapy over Fluticasone/vilanterol (Breo Ellipta)

 

When considering treatments for allergies, understanding the comparative advantage of each option is essential. Immunotherapy, often in the form of allergy shots or sublingual tablets, provides distinct benefits over the use of Fluticasone/vilanterol (Breo Ellipta).

 

Long-Term Benefits

 

  • Addressing Root Causes: Immunotherapy works by gradually desensitizing the immune system to specific allergens, targeting the underlying causes of allergy symptoms rather than just alleviating them temporarily.
  • Durability of Effects: Unlike Fluticasone/vilanterol, which requires continuous use for symptom control, immunotherapy can lead to long-term remission of allergy symptoms even after the treatment has been stopped.

 

Reduced Medication Dependence

 

  • Decreased Need for Medications: With successful immunotherapy, patients often experience a significant reduction in their need for other allergy medications, like Fluticasone/vilanterol, which can have side effects or require daily use.
  • Enhancing Overall Quality of Life: By reducing the dependency on daily medication, individuals can enjoy a more spontaneous lifestyle without the continuous burden of managing their allergy symptoms.

 

Considerations for Holistic Health

 

  • Improved Immune Function: Immunotherapy has the potential to alter the natural course of allergic disease by helping the immune system develop a tolerance to allergens, potentially preventing the progression of allergies to more severe forms such as asthma.
  • Lower Risk of Side Effects: While Fluticasone/vilanterol is generally well-tolerated, long-term use of corticosteroids can lead to side effects like hoarseness or oral thrush; immunotherapy typically avoids these issues, focusing instead on modifying the immune response.

 

In conclusion, immunotherapy offers profound, long-term benefits by addressing the root causes of allergies and reducing medication dependence. This makes it a preferable treatment approach for those seeking a more comprehensive solution to allergy management.

 

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Benefits of Curex

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5-30x higher cumulative dose vs allergy shots

Sublingual immunotherapy delivers a higher dose of allergens over the course of treatment.

Potential for results in as few as 6 months

Individual results vary but some users have reported a noticeable difference in as few as 6-12 months since starting treatments

Excellent safety profile

Studies that have been reviewed by certified physicians show that sublingual immunotherapy is a safe treatment option
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