Curex is the place to go for all your allergy questions and needs. Led by healthcare entrepreneurs and allergy clinicians, Curex is an integrated, online telemedicine clinic for people who suffer from environmental allergies (e.g., indoor, outdoor or pet), asthma, and eczema.

Curex is the largest online allergy and asthma clinic in the U.S. We started because our clinicians wanted to offer more convenient and affordable allergy and asthma care for everyone. So far we have attracted more than 50,000 customers from every U.S. state. We are proud to have the highest patient satisfaction and loyalty rates in the industry. Our service has been audited and certified by LegitScript.com.

What services do you offer?

Curex provides comprehensive care for those suffering from allergies, asthma, and eczema. This includes customized sublingual immunotherapy, at-home concierge allergy testing, and symptom management. Our goal is to provide accessibility and quality of allergy care in the U.S.

Does Curex accept insurance?

Curex accepts the majority of insurance plans across the United States, including Aetna, Anthem, United, Humana, and others. While it is difficult to estimate out-of-pocket costs prior to a claim being submitted, our team will work with you to make sure your treatment is as affordable as possible. For that purpose, we also cap copays at $500/year. In addition, Curex accepts HSA and FSA.

What conditions do you treat?

We focus on indoor and outdoor allergies caused by environmental or inhalant allergies, like those caused by pollens, weeds, grasses, dust mites, molds, and pets. We also treat allergic asthma and eczema, as these conditions are closely related to allergies.

What is immunotherapy?

Immunotherapy is a longstanding form of treatment that aims to meaningfully reduce the underlying cause of indoor/outdoor allergies and related conditions. It is frequently practiced by using allergen extracts for shots or allergy tablets. Treatment plans are customized to the individual patient based on medical profile, test results, and lifestyle needs.

Can my child use Curex?

Curex serves adults and children as young as 5 years old. Certain tests and treatments may be limited for younger kids. Start by answering the quiz, so that our clinicians can recommend the best testing and treatment options.

Does Curex treat food allergies?

Curex currently treats allergies to tree, weed, grass pollens, pet allergies, dust mites, mold, and cockroach. We do not treat food, metal, venom, or flower allergies.

What is your cancellation policy?

Treatments are shipped in 3-month installments in all plans. Cancellations are accepted prior to the next refill being compounded by the pharmacy (so you can get a partial refund on a prepayment plan). To cancel or pause subscriptions, please email our team at hi@getcurex.com.

How does allergy testing work?

Depending on your location, we send a phlebotomist (medical assistant) to your home or office for a simple blood draw (not a finger prick). This sample is then processed using hospital-grade technology to produce accurate results. In some areas, you may need to go into a local lab for your blood draw. We work with LabCorp and Quest Diagnostics. This is an IgE blood test that results in more accurate results compared to finger prick tests that are available online through some companies. This is not a skin scratch test where an allergist spends 30+ minutes injecting you with small doses of allergens to see if any swelling or reaction occurs.

Is sublingual immunotherapy safe?

Studies have shown a significantly lower risk for anaphylaxis relative to allergy shots, allowing you to take them in the comfort of your own home. If recommended by your Curex-affiliated clinician, or if you prefer, your first dose may be monitored to ensure proper usage. Clinicians will also assist in helping you manage any side effects that you may experience.

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Mepolizumab (Nucala) Overview: Benefits, Side Effects | Curex

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Explore the latest in allergy relief with our review of Mepolizumab (Nucala). We cover its effectiveness, side effects, and how it compares to other treatments. Perfect for those seeking a comprehensive overview in a concise format.

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Allergy Clinic

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50,000+
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Mepolizumab (Nucala) Overview: Category & Primary Use

Mepolizumab, marketed under the brand name Nucala, is a therapeutic agent used in the management of specific inflammatory conditions, and it falls under the category of monoclonal antibodies. This medication is specifically designed to target and inhibit interleukin-5 (IL-5), a cytokine involved in the inflammatory pathway of certain diseases.

Drug Category

Mepolizumab is classified as an anti-interleukin-5 monoclonal antibody. This category of drugs is designed to neutralize the action of IL-5, thereby reducing eosinophilic inflammation, which is a hallmark in several conditions.

Indications

This medication is primarily indicated for use in the treatment of severe eosinophilic asthma, a form of asthma characterized by elevated levels of eosinophils, a type of white blood cell. These cells play a crucial role in the inflammatory processes that exacerbate asthma symptoms.

Conditions Treated

Mepolizumab is approved for the treatment of severe eosinophilic asthma in adults and children aged six years and older, typically as an add-on maintenance therapy.
It is also used in the management of eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, which is a rare autoimmune condition that involves blood vessel inflammation.
The drug is indicated for hypereosinophilic syndrome (HES), a disorder characterized by persistently high levels of eosinophils.

Mepolizumab’s mechanism of action significantly aids in controlling symptoms and reducing exacerbations in these conditions, providing therapeutic benefits to individuals with challenging eosinophil-associated diseases.

Why settle for temporary relief? Try immunotherapy for lasting results!

Am I eligible?

What Conditions Does Mepolizumab (Nucala) Treat?

Mepolizumab, marketed as Nucala, is used to treat certain conditions that involve eosinophils, a type of white blood cell that can contribute to inflammation and damage in various parts of the body.

Severe Eosinophilic Asthma

Mepolizumab is primarily indicated for severe eosinophilic asthma, a type of asthma characterized by high eosinophil levels. It is used to reduce the occurrence of asthma attacks.

Eosinophilic Granulomatosis with Polyangiitis (EGPA)

This condition is a rare autoimmune disease that can cause inflammation of small-to-medium-sized blood vessels. Mepolizumab helps in managing the symptoms by targeting the eosinophils, reducing their levels and activity.

Hypereosinophilic Syndrome (HES)

HES is a group of rare blood disorders characterized by the overproduction of eosinophils. Mepolizumab is used to manage this condition by controlling eosinophil levels and mitigating disease symptoms.

Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

Mepolizumab can also be used as an add-on treatment for CRSwNP, where it helps reduce nasal polyp size, nasal congestion, and other related symptoms by targeting eosinophilic inflammation.

Find out if immunotherapy is right for you

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Mepolizumab (Nucala): Effectiveness and Advantages Overview

Mepolizumab (Nucala) is a biologic medication used primarily for the treatment of severe eosinophilic asthma, among other conditions. Its targeted mechanism offers several benefits to patients who suffer from this type of asthma and related ailments.

Targeted Therapy

Specific Action: Mepolizumab specifically targets and inhibits interleukin-5 (IL-5), a key factor in the growth, activation, and survival of eosinophils, which are white blood cells that can cause inflammation and damage tissues when present in excess.
Fewer Side Effects: By homing in on a specific immune pathway, mepolizumab tends to cause fewer side effects compared to broader spectrum immunosuppressants.

Improved Asthma Control

Frequent Symptom Relief: Patients often experience fewer asthma attacks and a reduction in day-to-day symptoms, leading to improved quality of life.
Reduced Oral Corticosteroid Use: Mepolizumab allows many patients to decrease their dependence on oral corticosteroids, which are associated with significant long-term side effects.

Convenience and Adherence

Ease of Administration: Administered as a subcutaneous injection once every four weeks, it provides a convenient dosing schedule that may improve adherence to the treatment plan.
Simplified Management: Patients can often administer it at home after proper instruction, reducing the need for frequent healthcare visits.

Wide Range of Application

Additional Indications: Besides severe eosinophilic asthma, mepolizumab is also approved for use in other eosinophil-driven diseases, such as eosinophilic granulomatosis with polyangiitis (EGPA).
Potential Off-Label Uses: Ongoing research continues to explore other conditions that may benefit from mepolizumab treatment due to its targeted immunological effects.

Patient-Centered Outcomes

Improved Overall Health: Patients often report better overall health and reduced hospital visits due to fewer exacerbations.
Enhanced Daily Function: With reduced symptoms, patients typically experience better daily functioning, including improved sleep and increased physical activity.

Clinical Support

Our team is here to help!

Dr. Neeta Ogden, MD

Curex is poised to revolutionize the way allergies are treated in America, expanding access to clinical care and treatments that can meaningfully improve patients quality of life.

Dr. Ravi Patel, VP Telemedicine

At Curex, our mission is to help people improve their health and quality of life by understanding their allergies and treating them at their source.We provide more than individualized prescription treatments; we provide individualized care.

Jill Hamburg, PA - C

Immunotherapy made simple. We enable patients to receive personalized allergy care on their own time. No more waiting rooms.

Dr. Chet Tharpe, Medical Director

Curex has set the standard for the virtual allergy experience. From the comfort of their home, patients nationwide are able to receive a personalized treatment plan from an experienced clinician, aimed at treating the source of their allergies, not just the symptoms.

Kayla Mardaga, NP

Curex offers convenient at-home allergy testing options. Our goal is to determine if a patient would benefit from immunotherapy and then customize a treatment plan that can reduce both the symptoms and the reliance on allergy medications.

Happy Customers

We love helping people!

Allie, Nevada

"I have two cats I can finally cuddle!"
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Cat and dog allergies

Zachary, Texas

“I can breathe through my nose for the first time in like 20 years!"

Dust and mold allergies

Erika, New York

“I've noticed less sneezing and shortness of breath.”

Tree and grass allergies

Richard, Texas

I love the convenience!
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Tree and cat allergies

Mepolizumab (Nucala) Side Effects: Common and Serious, When to Seek Help

Mepolizumab, marketed as Nucala, is a medication used primarily for the treatment of severe eosinophilic asthma and other conditions caused by high levels of eosinophils. While effective, it does come with potential side effects and necessitates certain safety precautions.

Possible Side Effects of Mepolizumab (Nucala)

Headache: It is common for patients to experience mild to moderate headaches.
Injection Site Reactions: Redness, pain, or discoloration around the injection site might occur.
Back Pain: Some individuals might report mild back discomfort.
Weakness or Fatigue: General feelings of fatigue may develop, potentially affecting normal activities.
Upper Respiratory Tract Infections: These could present as sore throat or nasal congestion.
Hypersensitivity Reactions: Rarely, allergic reactions such as swelling or difficulty breathing may occur.

Safety Precautions When Using Mepolizumab (Nucala)

Medical History: Inform your healthcare provider of any past medical issues, especially parasitic infections or serious infections.
Allergic Reactions: Be vigilant for signs of allergic responses, and seek immediate medical attention if symptoms like swelling occur.
Pregnancy: Discuss the potential risks and benefits with your doctor if you are pregnant or planning to become pregnant.
Live Vaccines: Avoid receiving live vaccines while on Mepolizumab, as it may affect the vaccine's efficacy.
Drug Interactions: Provide a full list of medications and supplements to the healthcare provider to avoid potential interactions.
Corticosteroid Adjustment: If you are currently on corticosteroids, do not alter the dosage without consulting your physician.

A safer solution to allergies: try immunotherapy today!

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Advantages of Immunotherapy over Mepolizumab (Nucala)

When considering the treatment of allergies, it is important to evaluate the advantages of immunotherapy over medications such as Mepolizumab (Nucala). Immunotherapy offers a more comprehensive approach to addressing the root cause of allergies compared to symptomatic relief offered by medications.

Addresses Root Cause

Long-term Solution: Immunotherapy modifies the immune system's response to allergens, targeting the underlying cause rather than only relieving symptoms.
Reduces Dependency: Over time, it helps to reduce or eliminate the need for medication, offering potential long-term relief.

Wide Range of Allergies

Broader Scope: Immunotherapy can treat a range of allergies such as pollen, dust mites, animal dander, and more, unlike Mepolizumab, which is primarily used for specific conditions like asthma.
Preventive Action: It can prevent the development of new allergies and halt the progression from allergic rhinitis to asthma.

Sustainability and Cost-Effectiveness

Reduced Healthcare Costs: With potential long-term remission and less reliance on medication, immunotherapy can lead to decreased healthcare spending in the long run.
Convenience and Compliance: Options such as sublingual immunotherapy are convenient, improving patient compliance and outcomes.

Few Side Effects

Minimal Side Effects: Unlike Mepolizumab, which can have side effects like headaches and injection site reactions, immunotherapy is generally well-tolerated with side effects typically limited to mild local reactions.
Customizable Treatment: It allows for personalized treatment strategies tailored to the individual's specific allergy profile.

Improvement in Quality of Life

Enhanced Daily Functioning: By effectively controlling allergy symptoms and triggering a more natural immune response, patients can experience a significant improvement in their daily activities.
Better Symptom Management: Unlike temporary relief from medications, immunotherapy can provide sustained relief, enhancing overall quality of life.

PREVENTION+

Prevents allergies long term

At-home treatment saves time

Treatment taken daily under the tongue

Evaluation & allergy test at home

Talk or text with your clinician, as needed

$49/month (copays may apply)

ALLERGY SHOTS

Prevents allergies long term

Commute to clinic every week

Treatment injected weekly by syringe

Evaluation and testing in the clinic

Clinical visits require scheduling

Surprise insurance bills and high copays

We Treat Food, Indoor & Outdoor Allergies

Tree Pollens

Weed Pollens

Cat Allergies

Dog Allergies

Dust Mites

Molds

Food Allergies

At-home Immunotherapy

Benefits of Curex

At-home treatment

Apply treatments in minutes from the comfort of your own home with under-the-tongue applications instead of shots or pills

5-30x higher cumulative dose vs allergy shots

Sublingual immunotherapy delivers a higher dose of allergens over the course of treatment.

Potential for results in as few as 6 months

Individual results vary but some users have reported a noticeable difference in as few as 6-12 months since starting treatments

Excellent safety profile

Studies that have been reviewed by certified physicians show that sublingual immunotherapy is a safe treatment option

Treatment prescribed
by clinician

Clinicaly made allergen extracts are customized for your allergies

Your immune system gets desensitized to allergens, giving you long-term relief.

FAQs

Curex provides allergy care plans for allergies, asthma, eczema and pet allergies.

Curex providers may prescribe sublingual allergy drops that contain the same ingredients as allergy shots but are more convenient & affordable.
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Curex-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Curex telehealth platform.

Compounded medications have not been approved by the FDA and the FDA has not evaluated their safety or efficacy.

Curex, Inc. All rights reserved.