How does the body's immune response to Needle Grass pollen change over time?

The body's immune response to Needle Grass pollen, or any other allergen, involves the production of antibodies that specifically recognize and bind to the allergen. Upon initial exposure to the pollen, the body responds by producing a type of antibody called Immunoglobulin E (IgE). These antibodies bind to immune cells called mast cells, sensitizing them to the allergen.

When repeat exposure to Needle Grass pollen occurs, the IgE antibodies attached to the mast cells recognize the pollen, triggering the mast cells to release inflammatory chemicals like histamine. This results in common allergy symptoms such as sneezing, itching, runny nose, and watery eyes.

Over time, repeated exposure to the pollen can lead to changes in the immune response. In some cases, the body may become desensitized to the allergen through a process called immune tolerance. This means that the immune system becomes less reactive to the allergen, leading to a reduction in allergy symptoms.

To achieve this, many allergy sufferers undergo immunotherapy, a treatment that exposes the body to gradually increasing doses of the allergen in an attempt to modify the immune response. If successful, over time, the immune system becomes less sensitive to the allergen, leading to fewer and less severe allergic reactions.

In other cases, rather than becoming desensitized, individuals can become more sensitive to the allergen over time, a phenomenon known as allergic sensitization. This can lead to more severe allergy symptoms and can also trigger asthma symptoms in some individuals.

It's important to note that each individual's immune response can differ significantly, which is why the severity and progression of allergies can vary so widely from person to person.