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Written and prepared by:
A Hoefges, SJ McIlwain, AK Erbe, N Mathers, A Xu, D Melby, K Tetreault, T Le, K Kim, RS Pinapati, B Garcia, J Patel, M Heck, AS Feils, N Tsarovsky, JA Hank, ZS Morris, IM Ong, PM Sondel
Explore the antibody landscape in C57BL/6 mice cured of B78 melanoma via immunotherapy. Utilizing a whole-proteome peptide array, this study identifies a broad repertoire of antibodies targeting linear peptide sequences in melanoma. The research demonstrates the immune memory's specificity and potential for enhancing immunotherapy effectiveness against cancer.
Comprehensive analysis of antibody responses in C57BL/6 mice cured of B78 melanoma through combined immunotherapy.
Using high-density peptide arrays to identify antibody targets in mice cured of melanoma via immunotherapy.
Study reveals a repertoire of antibodies against melanoma in mice following curative immunotherapy treatment.
Cross-validation of antibody binding sites using high-density peptide arrays, JPT multi-well arrays, and ELISA.
Research identifies key tumor antigens recognized by antibodies in melanoma-cured mice.
Study confirms reliability of high-density peptide arrays in detecting antibody responses in melanoma immunotherapy.
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