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Written and prepared by:
Theodore Kim, Richard L. Wasserman, Oral Alpan, Atul Shah, Douglas Jones
Explore the clinical utility of Basophil and B-cell biomarkers in monitoring disease activity for food allergies and oral immunotherapy. This study highlights the significance of CD63 and CD203c expression on basophils and CD73 expression on B cells in patients undergoing peanut oral immunotherapy (OIT). The research demonstrates that these biomarkers can potentially indicate desensitization and long-term immunological tolerance, aiding in better management and monitoring of peanut allergies.
Assessing basophil biomarkers' clinical utility for monitoring disease activity in food allergy patients undergoing oral immunotherapy.
Evaluating B-cell biomarkers to track immune changes in food allergy and oral immunotherapy patients.
Investigating the effects of peanut oral immunotherapy on basophil activation and immune response.
Study shows decreased CD63/CD203c ratio in basophils of patients undergoing peanut oral immunotherapy.
Analysis reveals significant changes in CD73 expression on B cells in peanut allergy and immunotherapy patients.
Highlighting the importance of immune monitoring in peanut oral immunotherapy to predict treatment success and manage complications.
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